The association between the renal resistive index and the myocardial performance index in the general population

Abstract

Objective The renal resistive index (RRI) is the most described measure of renal hemodynamics. The myocardial performance index (MPI) is widely used to assess overall myocardial performance. In this study, we aimed to investigate the relationship between renal hemodynamics, assessed by the RRI, and cardiac functions, assessed by the MPI in the general population. Methods This single‐center, cross‐sectional study included a total of 302 consecutive patients who presented to our outpatient cardiology clinic between October 2019 and February 2020. All patients underwent transthoracic echocardiography and renal Doppler ultrasonography. The study population was divided into two groups: low RRI group (RRI ≤ 0.7, n = 236) and high RRI group (RRI > 0.7, n = 66). Results E/A ratio, left ventricular ejection fraction (LVEF), and the MPI were significantly higher in the high RRI group than in the low RRI group (61.3 ± 15.4 vs 55.3 ± 16.4, P = .010 for E velocity; 0.9 ± 0.3 vs 0.7 ± 0.2, P = .008 for E/A ratio; 57.7 ± 4.7 vs 53.2 ± 10.1, P = .029 for LVEF; 0.52 ± 0.1 vs 0.43 ± 0.1, P < .001 for the MPI). A stepwise linear regression analysis demonstrated that LVEF (β = .123, P = .026), E velocity (β = .221, P < .001), and the MPI (β = .392, P < .001) were independently associated with the RRI. Conclusion Left ventricular ejection fraction and intra‐cardiac Doppler blood flow indices, including E velocity and the MPI, were significantly and independently associated with the RRI in the general population.

The Relationship Between Myocardial Performance Index and Renal Resistive Index in Resistant Hypertension

“…Tedesco et al (30) showed that high RRI (29). A study conducted by Quisi et al (31) showed a significant association between RRI and MPI in the general population. In a study, the association of renal hemodynamics with RHT was examined.…”

Current Insights into Renal Resistive Index Significance in Kidney and Cardiovascular Disease

“…However, central pulse pressure, diastolic trasmitral E and A Doppler flow velocities and velocity time integral of LV outflow tract have also strong correlation with RRI values [23]. More than that, not only that RRI depends on LVEF and myocardial performance index [95], but also it is an independent prognostic marker for atherosclerotic cardiovascular events in patients with preserved EF [96].…”

Current Insights into the Significance of the Renal Resistive Index in Kidney and Cardiovascular Disease

“…However, central pulse pressure, diastolic trasmitral E and A Doppler flow velocities, and the velocity time integral of the LV outflow tract also have strong correlation with RRI values [23]. Moreover, not only does the RRI depend on LVEF and the myocardial performance index [92], but it is also an independent prognostic marker for atherosclerotic cardiovascular events in patients with preserved EF [93].…”