The association of polymorphic sites in some genes with type 1 diabetes mellitus in a sample of Egyptian children

Vitamin D receptor gene polymorphisms and the risk of the type 1 diabetes: a meta-regression and updated meta-analysis

“…Overall, 29 case-control studies with 3723 cases and 5578 controls were analyzed for assessment of FokI polymorphism and T1DM risk. Of 29 studies, 15 studies were conducted in European countries [ 15 , 34 – 36 , 38 – 41 , 44 , 47 , 49 , 71 ], 9 studies were in Asian countries [ 33 , 42 , 45 , 46 , 48 , 54 – 57 ], 3 studies were in African population [ 51 – 53 ] and eventually one study in Australia [ 50 ] and one study in American population [ 43 ]. Among studies were performed in Europe, Audi et al [ 71 ] conducted an association study in different city of Spain (Barcelona and Navarra) and reported all data separately including genotype and allele frequency; thus we considered each population as a separate study.…”

“…It was detected that 15 studies with 1938 cases and 4450 controls were performed in European countries [ 15 , 34 – 36 , 38 , 40 , 41 , 44 , 49 , 59 , 60 , 71 ] which among these 15 studies, Turpeinen et al [ 36 ] conducted an association study in different city of Finland (Turku, Tampere and Oulu) and reported all data separately, including genotype and allele frequency; thus we considered each population as a separate study. Moreover, 13 studies out of 34 eligible studies were carried out in Asian populations [ 42 , 46 , 48 , 56 – 58 , 62 – 64 , 67 – 70 ], 3 studies were in Americans [ 43 , 61 , 66 ] and three studies were in Africans [ 52 , 53 , 65 ]. No significant association between BsmI polymorphism and T1DM risk were found under all genotype models for the overall population.…”

Vitamin D receptor gene polymorphisms and the risk of the type 1 diabetes: a meta-analysis based on 40 case–control studies

“…Overall, 29 case-control studies with cases and 5578 controls were analyzed for assessment of FokI polymorphism and T1DM risk. Of 29 studies, 15 studies were conducted in European countries [15,[34][35][36][37][38][39][40][41][42][43][44], 9 studies were in Asian countries [45][46][47][48][49][50][51][52][53], 3 studies were in African population [54][55][56] and eventually one study in Australia [57] and one study in American population [58]. Among studies were performed in Europe, Audi et al [37] conducted an association study in different city of Spain (Barcelona and Navarra) and reported all data separately including genotype and allele frequency; thus we considered each population as a separate study.…”

“…It was detected that 15 studies with 1938 cases and 4450 controls were performed in European countries [15, 34-38, 40-42, 44, 59, 60] which among these 15 studies, Turpeinen et al [36] conducted an association study in different city of Finland (Turku, Tampere and Oulu) and reported all data separately, including genotype and allele frequency; thus we considered each population as a separate study. Moreover, 14 studies out of 35 eligible studies were carried out in Asian populations [46,48,49,52,53,[61][62][63][64][65][68][69][70][71], 3 studies were in Americans [58,67,72] and three studies were in Africans [54,56,66] Table 3.…”

Vitamin D receptor gene polymorphisms and the risk of the type 1 diabetes: a meta-analysis based on 40 case–control studies

“…Overall, 29 case-control studies with 3723 cases and 5578 controls were analyzed for assessment of FokI gene polymorphism and T1DM risk. Of 29 studies, 15 studies were conducted in European countries [14,[29][30][31][32][33][34][35][36][37][38][39], 9 studies were in Asian countries [40][41][42][43][44][45][46][47][48], 3 studies were in African population [49][50][51] and eventually one study in Australia [52] and one study in American population [53]. Among studies were performed in Europe, Audi et al [32] conducted an association study in different city of Spain (Barcelona and Navarra) and reported all data separately including genotype and allele frequency; thus we considered each population as a separate study.…”