The Asthma Control TestTM (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey

Abstract

Aims: To evaluate whether the Asthma Control Test TM (ACT) score is predictive of Global Initiative for Asthma (GINA) guideline-defined classification levels of asthma control. The ACT is a validated, 5-item, patient-completed measure of asthma control with a recall period of four weeks.Methods: Cross-sectional survey comparing ACT score and GINA classification of asthma control among 2949 patients attending primary care physicians and specialists in France, Germany, Italy, Spain, the UK, and the USA. Results:The area under the receiver operating characteristics curve for ACT score predicting GINA control was 0.84 (95% CI 0.82-0.85). An ACT score of <19 (not well-controlled asthma) correctly predicted GINA-defined partly controlled/uncontrolled asthma 94% of the time, while an ACT score of >20 predicted GINA-defined controlled asthma 51% of the time, with kappa statistic of 0.42, representing moderate agreement.Conclusions: An ACT score <19 is useful for identifying patients with poorly controlled asthma as defined by GINA.

The Asthma Control Test (ACT) as an alternative tool to Global Initiative for Asthma (GINA) guideline criteria for assessing asthma control in Vietnamese outpatients

“…2 Guideline-defined asthma control can be achieved and maintained for the majority of patients in controlled trial settings. [3][4][5] In Vietnam, the GINA guidelines were recently used as the main reference source for the national asthma guidelines. 1 A recent study suggested that the level of asthma control in Vietnam is poorer than expected, with less than 1% of patients studied meeting the definition of asthma control.…”

Asthma Control Assessment Tools

“…9,13,25,30 A cutoff score of Յ19 was associated with higher risk of adverse asthma outcomes, such as asthma exacerbation 17,31 and urgent health-care utilization. 17,32 With regard to NAEPP EPR-3 guidelines, a score of Ն20 indicates well-controlled asthma, a score of 16 -19 indicates not well-controlled asthma, and a score of Յ15 indicates very poorly controlled asthma.…”

Choice of basic therapy for asthma in real clinical practice

“…Опрос с использованием балльной оценки симптомов по опросникам Asthma Control Test (ACT) и Asthma Control Questionnaire (ACQ) является более чувствительным при оценке из-менения уровня контроля симптомов БА [4,5].…”