The AUDIT questionnaire: choosing a cut-off score

Conigrave, Katherine M.; Hall, Wayne; Saunders, John B.

doi:10.1111/j.1360-0443.1995.tb03552.x

Cited by 487 publications

(228 citation statements)

References 11 publications

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“…19 Frequency of current alcohol use was assessed with the first item from the Alcohol Use Disorders Identification Test. 20 Participants also indicated whether they used marijuana, cocaine, methamphetamine, and other drugs in the previous month. Because frequencies of drug use were low in our sample, we created an index for drug use by summing the number of different nonalcohol drugs that were used in the previous month.…”

Section: Methodsmentioning

confidence: 99%

Health and Treatment Implications of Food Insufficiency among People Living with HIV/AIDS, Atlanta, Georgia

et al. 2010

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HIV/AIDS is concentrated among the inner-city poor and poverty may directly interfere with HIV treatment. This study examined food insufficiency in relation to HIV-related health and treatment. A sample of 344 men and women living with HIV/ AIDS in Atlanta, Georgia completed measures of food security, health, and HIV disease progression and treatment. HIV treatment adherence was monitored using unannounced pill counts. Results showed that half of people living with HIV/AIDS in this study lacked sufficient food, and food insufficiency was associated with multiple indicators of poor health, including higher HIV viral loads, lower CD4 cell counts, and poorer treatment adherence. Adjusted analyses showed that food insufficiency predicted HIV treatment non-adherence over and above years of education, employment status, income, housing, depression, social support, and non-alcohol substance use. Hunger and food insecurity are prevalent among people living with HIV/AIDS, and food insufficiency is closely related to multiple HIV-related health indicators, particularly medication adherence. Interventions that provide consistent and sustained meals to people living with HIV/AIDS are urgently needed.

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Section: Methodsmentioning

confidence: 99%

Health and Treatment Implications of Food Insufficiency among People Living with HIV/AIDS, Atlanta, Georgia

et al. 2010

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“…Drinking habits were assessed by questionnaires on lifetime drinking history and self-administered AUDIT C test [19,20]. Patients with normal values of one liver enzyme at baseline (T 0 ) were not excluded.…”

Section: Trial Designmentioning

confidence: 99%

Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: A randomized controlled trial

Loguercio

Andreone

Brisc

et al. 2012

Free Radical Biology and Medicine

219

147

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The only currently recommended treatment for nonalcoholic fatty liver disease (NAFLD) is lifestyle modification. Preliminary studies of silybin showed beneficial effects on liver function. Realsil (RA) comprises the silybin phytosome complex (silybin plus phosphatidylcholine) coformulated with vitamin E. We report on a multicenter, phase III, double-blind clinical trial to assess RA in patients with histologically documented NAFLD. Patients were randomized 1:1 to RA or placebo (P) orally twice daily for 12 months. Prespecified primary outcomes were improvement over time in clinical condition, normalization of liver enzyme plasma levels, and improvement of ultrasonographic liver steatosis, homeostatic model assessment (HOMA), and quality of life. Secondary outcomes were improvement in liver histologic score and/or decrease in NAFLD score without worsening of fibrosis and plasma changes in cytokines, ferritin, and liver fibrosis markers. We treated 179 patients with NAFLD; 36 were also HCV positive. Forty-one patients were prematurely withdrawn and 138 patients analyzed per protocol (69 per group). Baseline patient characteristics were generally well balanced between groups, except for steatosis, portal infiltration, and fibrosis. Adverse events (AEs) were generally transient and included diarrhea, dysgeusia, and pruritus; no serious AEs were recorded. Patients receiving RA but not P showed significant improvements in liver enzyme plasma levels, HOMA, and liver histology. Body mass index normalized in 15% of RA patients (2.1% with P). HCV-positive patients in the RA but not the P group showed improvements in fibrogenesis markers. This is the first study to systematically assess silybin in NAFLD patients. Treatment with RA but not P for 12 months was associated with Free

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“…AUDIT total scores can range from 0 to 40, and scores of 8 or higher have been used to identify individuals who may be at risk for, or who are experiencing, alcohol-related problems. 26 The DAST-20 is a 20-item shortened version of the 28-item DAST designed to identify drug-use related problems. 13 This shortened version has demonstrated high internal consistency.…”

Section: Instruments and Assessmentmentioning

confidence: 99%

Validation of the Alcohol Use Disorders Identification Test and the Drug Abuse Screening Test in First Episode Psychosis

2008

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W La Revue canadienne de psychiatrie, vol 53, no 1, janvier 2008 26 Objective: To determine the validity and reliability of the Alcohol Use Disorders Identification Test (AUDIT) and Drug Abuse Screening Test (DAST) for detecting alcohol and drug use disorders, respectively, in a population with first-episode psychosis (FEP). Method:Subjects with FEP completed the AUDIT and DAST and were divided into groups according to the presence or absence of a Structured Clinical Interview for DSM-IV (SCID) diagnosis of either current alcohol or drug misuse. The data were analyzed to see whether AUDIT and DAST scores were predictive of SCID diagnosis. Results:Patients with alcohol-related SCID diagnoses and those with drug-related SCID diagnoses scored significantly higher on the AUDIT and DAST, respectively, than the group without the respective SCID diagnosis (P < 0.001 in both cases). The AUDIT functioned best with a problem drinking cut-off score of 10 (sensitivity, 85%; specificity, 91%). The DAST functioned best with a problem drug use cut-off score of 3 (sensitivity, 85%; specificity, 73%). The area under the receiver operating characteristic curve was 0.86 for the AUDIT and 0.83 for the DAST. Conclusion:The DAST and AUDIT may reliably identify FEP patients with substance abuse. Can J Psychiatry 2007;53(1):26-33Information on funding and support and author affiliations appears at the end of the article. Clinical Implications· Given the efficacy of the AUDIT and DAST in patients with FEP, clinicians should be able to screen for substance use disorders quickly and regularly, with minimal burden on resources. · This might promote better monitoring of substance use disorders in this population, which is prone to adverse consequences from such use. · These instruments function better in a population with FEP when cut-off scores are altered to better suit this population. Limitations· AUDIT cut-off points are less precise because there were few subjects with problem drinking. A slightly larger sample might have helped in this regard. · One-third of the total catchment area sample either refused treatment and (or) refused consent to participate in this study, limiting somewhat the generalizability of these findings. Data analyzed derived solely from scores on the AUDIT and DAST administered to patients at baseline. Other time points in treatment were not examined.

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The AUDIT questionnaire: choosing a cut-off score

Cited by 487 publications

References 11 publications

Health and Treatment Implications of Food Insufficiency among People Living with HIV/AIDS, Atlanta, Georgia

Health and Treatment Implications of Food Insufficiency among People Living with HIV/AIDS, Atlanta, Georgia

Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: A randomized controlled trial

Validation of the Alcohol Use Disorders Identification Test and the Drug Abuse Screening Test in First Episode Psychosis

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