The Biophysical Organization of the System of the Cerebral Circulation

Moskalenko, Yu. E.; Weinstein, G. B.; Demchenko, Ivan T.; Kislyakov, Yu. Ya.; Кривченко, А. И.

doi:10.1016/b978-0-08-022672-9.50006-0

Cited by 9 publications

(13 citation statements)

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“…(1980) reported activation in the SMA and not in the primary motor cortex, in contrast to our results. with similar effects on CBF (Hudetz et ai., 1992) and brain tissue POz (Cooper et al, 1966;Halsey and McFarland, 1976;Moskalenko, 1980) Not only were fluctuations suppressed by hyper capnia in a similar manner in the present study and previous animal studies, but also the time course of the MRI response to hypercapnia was quite similar to that seen in regional CBF to the same stimulus . The gradient recalled T2*-weighted EPI pulse sequence is sensitive to both blood oxygen ation and blood flow.…”

Section: Discussionsupporting

confidence: 86%

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Hypercapnia Reversibly Suppresses Low-Frequency Fluctuations in the Human Motor Cortex during Rest Using Echo–Planar MRI

Biswal¹,

Hudetz²,

Yetkin

et al. 1997

J Cereb Blood Flow Metab

156

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Summary: Using magnetic resonance (MR) echo-planar imaging (EPI), we recently demonstrated the prescnce of low-frequency fluctuations «0,1 Hz) in MR signal inten sity from thc resting human brain that have a high degree of temporal correlation (p < 103) within and across associ ated regions of the sensorimotor cortex, These fluctuations in MR signal intensity are belicved to arise from fluctua tions in capillary blood flow and oxygenation, A substantial overlap between the activation map generated by bilateral finger tapping and temporally-correlated voxels from the sensorimotor oortex obtained during rest was observed, In the work reported here, we investigated whether respira tory hypercapnia, which is known to suspend spontane ous oscillations in regional cerebral blood flow, influences these low-frequency fluctuations, The magnitude of low- 301frequency fluctuations was reversibly diminished during hypercapnia, reSUlting in a substantial decrease of the tem poral correlation both within and across contralateral hemi spheres of the sensorimotor cortex, After the breathing mixture was returned to ambient air, the magnitude and spatial extent of the temporal correlation of low-frequency fluctuations returned to normaL Results of this study sup port the hypothesis that low-frequency

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Section: Discussionsupporting

confidence: 86%

“…1988), and polarographic measurement of brain tis sue P02 with microelectrodes (Moskalenko, 1980;Cooper et aI., 1966;Halsey and McFarland, 1974). Hudetz et aI.…”

mentioning

confidence: 99%

Hypercapnia Reversibly Suppresses Low-Frequency Fluctuations in the Human Motor Cortex during Rest Using Echo–Planar MRI

Biswal¹,

Hudetz²,

Yetkin

et al. 1997

J Cereb Blood Flow Metab

156

View full text Add to dashboard Cite

show abstract

“…In this study, the effect of neither mannitol nor nitroglycerine on MCA V mean was identifiable. NIRS monitors regional cerebral oxygenation and S c O 2 reflects a mixed vascular saturation and it is dominated by venous blood which contributes to approximate 75% of cerebral blood volume 26 . However, there are concerns over its accuracy, interpretation and reliability 27,28 and its clinical application is still under investigation.…”

Section: Discussionmentioning

confidence: 99%

Middle Cerebral Artery Flow Velocity and Cerebral Oxygenation during Abdominal Aortic Surgery

Liu

Burcev

Pott

et al. 1999

Anaesth Intensive Care

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Cerebral perfusion was evaluated in twelve patients undergoing elective infra-renal abdominal aortic aneurysmectomy by transcranial Doppler ultrasonography-determined middle cerebral artery mean flow velocity, near-infrared spectroscopy-assessed cerebral oxygen saturation and systemic haemodynamic variables. The middle cerebral artery mean flow velocity and cerebral oxygen saturation decreased during cross-clamping of the aorta, and both increased upon declamping of the aorta with the oxygen saturation change lagging behind the change in the flow velocity. The changes in cerebral flow velocity and oxygen saturation paralleled the deviations in cardiac output and end-tidal carbon dioxide tension.

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“…Spontaneous low-frequency oscillations have been observed in the regional cerebral blood flow and oxygenation of animals and humans using many different techniques, including laser Doppler flow (Golanov, Yamamoto, & Resi, 1994; Hudetz, Smith, Lee, Bosnjak, & Kampine, 1995), fluororeflectometry (Dora & Kovach, 1981; Vern, Schuette, Leheta, Juel, & Radulovacki, 1988), fluorescence video microscopy (Biswal & Hudetz, 1996), polarographic measurement of brain tissue (Cooper, Crow, Walter, & Winter, 1966; Halsey & McFarland, 1974; Moskalenko, 1980), and near infrared spectroscopy (Obrig et al, 2000). …”

Section: Approaches To Measuring Brain Connectivitymentioning

confidence: 99%

Modern Methods for Interrogating the Human Connectome

Lowe

Sakaie

Beall

et al. 2016

J Int Neuropsychol Soc

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Objective Connectionist theories of brain function took hold with the seminal contributions of Norman Geschwind a half century ago. Modern neuroimaging techniques have expanded the scientific interest in the study of brain connectivity to include the intact as well as disordered brain. Method In this review, we describe the most common techniques used to measure functional and structural connectivity, including resting state functional MRI, diffusion MRI, and electroencephalography and magnetoencephalography coherence. We also review the most common analytical approaches used for examining brain interconnectivity associated with these various imaging methods. Results This review presents a critical analysis of the assumptions, as well as methodological limitations, of each imaging and analysis approach. Conclusions The overall goal of this review is to provide the reader with an introduction to evaluating the scientific methods underlying investigations that probe the human connectome.

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The Biophysical Organization of the System of the Cerebral Circulation

Cited by 9 publications

References 0 publications

Hypercapnia Reversibly Suppresses Low-Frequency Fluctuations in the Human Motor Cortex during Rest Using Echo–Planar MRI

Hypercapnia Reversibly Suppresses Low-Frequency Fluctuations in the Human Motor Cortex during Rest Using Echo–Planar MRI

Middle Cerebral Artery Flow Velocity and Cerebral Oxygenation during Abdominal Aortic Surgery

Modern Methods for Interrogating the Human Connectome

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