The Bone Scan in Metastatic Disease

Fogelman, Ignac; McKillop, James H.

doi:10.1007/978-1-4471-3254-7_3

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Diagnosing Metastatic Bone Disease1

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2004

2024

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Cited by 7 publications

(1 citation statement)

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“…Even following excessive pre-treatment with bisphosphonates, bone scans do not produce false-negative results [13]. However, increased bone remodeling can also be caused by other diseases affecting the bone (e.g., inflammation or fracture) [14]. These conditions decrease the specificity of the SS.…”

Section: Diagnosing Metastatic Bone Diseasementioning

confidence: 99%

Treatment Options for Breast Cancer and Bone Metastases

Pecherstorfer

2009

Womens Health (Lond Engl)

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The most common destination for breast cancer metastases is bone. If bone metastases are detected, treatment algorithms should include the continuation of cytoreductive therapy with the addition of treatment to counter skeletal-related events, including bone pain. The range of current treatment options includes bisphosphonates, surgical intervention to improve structural integrity and palliative focal radiotherapy. This article focuses on the role of bisphosphonate therapy in metastatic breast cancer. Bisphosphonate therapy significantly reduces the impact of skeletal-related events, reduces bone pain and increases patient quality of life. Our current understanding is that bisphosphonates may also disrupt the metastatic process and reduce the development of bone lesions. Ultimately, this may lead to further expansion of bisphosphonate-based therapy in the future.

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Section: Diagnosing Metastatic Bone Diseasementioning

confidence: 99%