The burden and predisposing factors of non-communicable diseases in Mashhad University of Medical Sciences personnel: a prospective 15-year organizational cohort study protocol and baseline assessment

Tohidinezhad, Fariba; Khorsand, Ali; Zakavi, Seyed Rasoul; Rezvani, Reza; Zarei‐Ghanavati, Siamak; Abrishami, Majid; Moradi, Ali; Tavakoli, Majid; Farrokh, Donya; Rad, Masoud Pezeshki; Abbasi, Bita; Ahadi, Mitra; Saleh, Lahya Afshari; Tayebi, Maryam; Amini, Mahnaz; Abu‐Hanna, Ameen; Eslami, Saeid

doi:10.1186/s12889-020-09704-3

Cited by 22 publications

(22 citation statements)

References 35 publications

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“…Our control group was recruited from healthy personnel of MUMS, as part of a longitudinal cohort study, PERSIAN Organizational Cohort study in MUMS. [35] The controls were evaluated and OCTA images were acquired to build a local normal OCTA normative database and cohort analysis. The individuals in the control group were examined when no COVID-19 cases were formally reported in Iran in 2019.…”

Section: Discussionmentioning

confidence: 99%

Optic Nerve Head Optical Coherence Tomography Angiography Findings after Coronavirus Disease

Abrishami

Daneshvar

Emamverdian

et al. 2021

JOVR

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Purpose: To quantify the microvasculature density of the optic nerve head (ONH) using optical coherence tomography angiography (OCTA) analysis in patients recovered from Coronavirus Disease 2019 (COVID-19). Methods: In a comparative cross-sectional, observational study, patients recovered from COVID- 19 whose initial diagnosis was confirmed by an rRT-PCR of a nasopharyngeal sample were included in this study. OCTA of ONH was performed in included patients and normal controls. Vascular density (VD) of the all vessels (AV) and small vessels (SV) inside the disc and radial peripapillary capillary (RPC) network density was measured in COVID-19 recovered patients and compared with similar parameters in an age-matched group of normal controls. Results: Twenty-five COVID-19 patients and twenty-two age-matched normal controls were enrolled in the study and one eye per participant was evaluated. The mean whole image SV VD in the COVID-19 group (49.31 ± 1.93) was not statistically significantly different from that in the control group (49.94 ±. 2.22; P = 0.308). A decrease in RPC VD was found in all AV and SV VD measured, which became statistically significant in whole peripapillary SV VD, peripapillary inferior nasal SV VD, peripapillary inferior temporal SV VD, peripapillary superior nasal SV VD, and grid-based AV VD inferior sector (P < 0.05). Inside disc SV VD in the COVID-19 group (49.43 ± 4.96) was higher than in the control group (45.46 ± 6.22) which was statistically significant (P = 0.021). Conclusion: Unremarkable decrease was found in ONH microvasculature in patients who had recovered from COVID-19. These patients may be at risk of ONH vascular complications. Increase in inner disc SV VD may be an indicator of ONH hyperemia and edema.

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Section: Discussionmentioning

confidence: 99%

Optic Nerve Head Optical Coherence Tomography Angiography Findings after Coronavirus Disease

Abrishami

Daneshvar

Emamverdian

et al. 2021

JOVR

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“…Geospatial analysis that is conducted by the geographical information system (GIS) help researchers and policymakers to analyze, identify, and visualize geographical patterns of diseases [ 26 – 28 ]. Thus, in this study, we used GIS to link and quantify risk factors to describe and provide a geodatabase of the PERSIAN Organizational Cohort study [ 29 ], as a set of individual and socio-environmental factors, to determine the blood pressure level of people living in Mashhad City in 2018. This geodatabase is a practical tool to identify high-risk areas of hypertension and exploring socio-environmental factors in future studies for managing resources and implementing targeted interventions [ 30 ].…”

Section: Objectivementioning

confidence: 99%

“…In this study, 5938 samples were obtained through the PERSIAN Cohort study in Mashhad [ 29 ]. The city of Mashhad is the second most populous city in Iran, located in the northeast of the country [ 31 ].…”

Section: Data Descriptionmentioning

confidence: 99%

A geodatabase of blood pressure level and the associated factors including lifestyle, nutritional, air pollution, and urban greenspace

et al. 2021

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Objectives Hypertension is a prevalent chronic disease globally. A multifaceted combination of risk factors is associated with hypertension. Scientific literature has shown the association among individual and environmental factors with hypertension, however, a comprehensive database including demographic, environmental, individual attributes and nutritional status has been rarely studied. Moreover, an integrated spatial-epidemiological approach has been scarcely researched. Therefore, this study aims to provide and describe a geodatabase including individual-based and socio-environmental data related to people living in the city of Mashhad, Iran in 2018. Data description The database has been extracted from the PERSIAN Organizational Cohort study in Mashhad University of Medical Sciences. The data note includes three shapefiles and a help file. The shapefile format is a digital vector storage format for storing geometric location and associated attribute information. The first shapefile includes the data of population, air pollutants and amount of available green space for each census block of the city. The second shapefile consists of aggregated blood pressure data to the census blocks of the city. The third shapefile comprises the individual characteristics data (i.e., demographic, clinical, and lifestyle). Finally, the fourth file is a guide to the previous data files for users.

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“…Therefore, we investigated this hypothesis in a large population in Iran to demonstrate whether this association is established or not. [15]. This study was planned to recruit 12,000 employees (aged 30-70 years) in Mashhad, northeast of Iran.…”

Section: Introductionmentioning

confidence: 99%

The Association between Anthropometry Indices and Serum Concentrations of Gamma-Glutamyl Transferase, Alkaline Phosphatase, Alanine Aminotransferase, and Aspartate Aminotransferase

Sobhani

Aryan

AkbariRad

et al. 2021

BioMed Research International

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Background. Nowadays, metabolic syndrome (MetS) has become a great public health crisis that threatens too many lives worldwide. Many previous studies have been investigated the association between MetS and anthropometric indices. This study is aimed at investigating the association between anthropometric indices with gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), alanine aminotransferase (ALT), and aspartate aminotransferase (AST). We were using data from a large population-based cohort of seemingly healthy women and men. Methods. A total of 7216 participants were included in this study. The serum levels of GGT, ALP, ALT, and AST with bioimpedance measures were obtained at the time of enrollment. Multiple regression analysis was performed to assess the relationship between anthropometric indices and serum levels of the aforementioned laboratory tests. Results. Serum levels of GGT, ALP, ALT, and AST significantly correlated with body mass index (BMI). Only ALP had a significant association with visceral fat area (VFA). AST, ALT, and ALP levels had a positive correlation with 50 kHz whole-body phase. Conclusion. From the findings of this study, body mass index consistently appeared a good predictor of elevated hepatic enzymes and triglycerides. Thus, it can be helpful in clinical settings to identify patients at risk of nonalcoholic fatty liver disease, which is closely related to metabolic syndrome.

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The burden and predisposing factors of non-communicable diseases in Mashhad University of Medical Sciences personnel: a prospective 15-year organizational cohort study protocol and baseline assessment

Cited by 22 publications

References 35 publications

Optic Nerve Head Optical Coherence Tomography Angiography Findings after Coronavirus Disease

Optic Nerve Head Optical Coherence Tomography Angiography Findings after Coronavirus Disease

A geodatabase of blood pressure level and the associated factors including lifestyle, nutritional, air pollution, and urban greenspace

The Association between Anthropometry Indices and Serum Concentrations of Gamma-Glutamyl Transferase, Alkaline Phosphatase, Alanine Aminotransferase, and Aspartate Aminotransferase

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