The case of an explanted 16-year-old mitral Carpentier-Edwards pericardial bioprosthesis

A Carpentier-Edwards pericardial (CEP) bioprosthesis was explanted from an 81-year-old woman due to nonstructural dysfunction 9 years after mitral valve replacement. The nonstructural dysfunction produced severe regurgitation in the mitral position. During the surgery, excessive pannus overgrowth was seen on the left ventricular side of the CEP bioprosthesis. Pannus overgrowth was prominent on one leaflet. That leaflet was stiff and shortened due to the excessive overgrowth of pannus. In this patient, the distortion of one leaflet was the main reason for transvalvular leakage of the CEP bioprosthesis in the mitral position. A new CEP bioprosthesis was implanted in the mitral position. Pathological analysis revealed fibrotic pannus with a small amount of cellular material over the leaflets of the resected CEP valve. This change was marked on the distorted leaflet.

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A case of Carpentier–Edwards pericardial bioprosthesis in mitral position explanted 22 years after implantation

Kubota

Wakasa

Ōoka

et al. 2010

J Artif Organs

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A case of Carpentier-Edwards PERIMOUNT (CEP) mitral pericardial bioprosthesis explanted 22 years after the valve replacement is reported. This patient underwent the previous replacement at the age of 50. The extracted bioprosthesis showed three rigid leaflets, one of which had a tear causing severe mitral regurgitation. The X-ray demonstrated calcification of varied extent among these leaflets, ranging from none to severe. When leaflet calcification is suppressed, perhaps the lifespan of a CEP valve can be prolonged more than previously expected. When a literature search was conducted, this case was found to represent the longest reported interval from the implantation of a CEP valve in the mitral position to the explantation as a result of severe mitral regurgitation caused by structural valve deterioration (SVD).

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The case of an explanted 16-year-old mitral Carpentier-Edwards pericardial bioprosthesis

Cited by 3 publications

References 7 publications

Journal of Artificial Organs 2006: the year in review

Journal of Artificial Organs 2006: the year in review

Pannus overgrowth after mitral valve replacement with a Carpentier-Edwards pericardial bioprosthesis

A case of Carpentier–Edwards pericardial bioprosthesis in mitral position explanted 22 years after implantation

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