The Changing Epidemiology and Emerging Patterns of Dermatophyte Species

Rippon, John W.

doi:10.1007/978-1-4613-9547-8_8

Cited by 122 publications

(76 citation statements)

References 36 publications

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“…Greek Physicians knew about ringworm infections in humans [2]. The factors affecting the distribution and transmission of dermatophytoses are largely dependent on the source of infection-zoophilic, geophilic and anthrophilic [3]. The inflammatory response to dermatophytes varies.In zoophilic and geophilic dermatophytes elicit a brisk inflammatory response in skin and hair follicles.…”

Section: Introductionmentioning

confidence: 99%

A Mycological Study of Superficial Mycoses at the Skin Clinic in Sabah, Malaysia

Mustafa¹,

Rajainthran²,

George³

2014

IJPSI

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Superficial fungal infections are common in Sabah. The skin clinic is a tertiary referral center for dermatological diseases in Sabah, and sees more than 7,000 cases of various skin complaints annually. The study analyses data collated from the skin clinic's medical records as well as fungus culture results from the microbiology diagnostic unit. A total of 7325 subjects were screened for superficial mycoses. Of the 7,325 subjects sampled randomly, 180 (2.5 %) had lesions suggestive of superficial mycoses. A predominance of dermatomatophytoses in the 50 years and above age group was observed. In Sabah State the relative humidity fluctuates between 60 % and 70 % for most part of the year and the area receives heavy rain falls. Thus, the environmental conditions are conducive for development of superficial mycoses.

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Section: Introductionmentioning

confidence: 99%

A Mycological Study of Superficial Mycoses at the Skin Clinic in Sabah, Malaysia

Mustafa¹,

Rajainthran²,

George³

2014

IJPSI

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“…This probably is a result of our soft "naked" stratum corneum, the wearing of clothing and shoes and our gregarious behavior 45 .…”

Section: Introductionmentioning

confidence: 99%

“…The distribution and frequency of dermatophytosis and their etiologic agents vary according to the geographic region studied, the socio-economic level of the population, the time of study, the climatic variations, the presence of domestic animals, and age 45 .…”

Section: Introductionmentioning

confidence: 99%

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Dermatophyte agents in the city of São Paulo, from 1992 to 2002

Chimelli

Sofiatti

Nunes

et al. 2003

Rev. Inst. Med. trop. S. Paulo

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SUMMARYDermatophytosis are superficial mycoses caused by fungi that can invade stratum corneum and keratinized tissues. In order to study the frequency of dermatophytes species and the clinical manifestations caused by these fungi, in São Paulo, SP, Brazil, the authors analyzed cultures isolated at the Mycology Laboratory from a selected population (15,300 out-patients of the Hospital das Clínicas, Department of Dermatology, Faculty of Medicine of University of São Paulo) from January 1992 to June 2002.The most prevalent dermatophyte was Trichophyton rubrum (48.7%), followed by Microsporum canis (20.9%), Trichophyton tonsurans (13.8%), Trichophyton mentagrophytes (9.7%), Epidermophyton floccosum (4.1%), and Microsporum gypseum (2.5%). These agents determined more than one clinical manifestation, i.e., tinea corporis (31.5%), tinea capitis (27.5%), tinea unguium (14.8%), tinea cruris (13.9%), tinea pedis (9.9%), and tinea manuum (1.9%). Clinical variants of dermatophytosis and their relationship to the etiologic agents were studied and the results were compared to those obtained in previous studies in other regions of Brazil and in other countries.

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“…1 Among the species of anthropophilic dermatophytes, Trichophyton rubrum is the most adapted to human beings and is one of the most important agents of tinea unguium, tinea pedis, tinea manuum, tinea corporis, and tinea capitis. [2][3][4][5][6][7][8][9][10] Treatment with topical antimycotics are generally not indicated for hyperkeratotic type tinea pedis and onychomycoses. In these cases, griseofulvine and, more recently, itraconazole and terbinafine have been frequently administered.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Sensitivity of Dermatophytes to Urea

Martins

Corim

Arriagada

et al. 2006

Clinics

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Martins JEC, Corim SM, Arriagada GLH, Melo NT de, Heins EM. In vitro sensitivity of dermatophytes to urea. Clinics. 2006;61(1):9-14.OBJECTIVE: Urea is commonly used as a keratolytic substance in the treatment of onychomycoses to improve the penetration of antifungal drugs in the lesion sites. The aim of the present study was to investigate the inhibitory action of urea on samples of dermatophytes in vitro. METHOD: Minimum inhibitory concentration of urea was determined for 31 samples of dermatophytes cultured in Sabourauddextrose broth containing different concentrations (7.5% up to 40%) of urea. Absence of growth was the criterion adopted to determine the minimum inhibitory concentration. RESULTS:The majority of samples (87%) were sensitive to urea at 12.5%, or less. 2 isolates of Trichophyton tonsurans and 2 of Trichophyton rubrum required 30%, and 40% urea, respectively, to be completely inhibited. CONCLUSION:In vitro results demonstrate inhibitory activity of urea on dermatophytes, suggesting that it could be used as an adjuvant in topical treatments.

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The Changing Epidemiology and Emerging Patterns of Dermatophyte Species

Cited by 122 publications

References 36 publications

A Mycological Study of Superficial Mycoses at the Skin Clinic in Sabah, Malaysia

A Mycological Study of Superficial Mycoses at the Skin Clinic in Sabah, Malaysia

Dermatophyte agents in the city of São Paulo, from 1992 to 2002

In Vitro Sensitivity of Dermatophytes to Urea

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