The Changing Epidemiology of Multiple Births in the United States

Russell, Rebecca; Petrini, Joann; Damus, Karla; Mattison, Donald R.; Schwarz, Richard H.

doi:10.1097/00006250-200301000-00025

Cited by 53 publications

(61 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other studies [10][11][12][13][14][15] have evaluated outcomes of triplet or highergestation infants in comparison to twins, but they had small sample sizes and none of them had evaluated ELBW infants exclusively. Russell et al, 5 using National Center for Health Statistics data, showed that the mortality rate for very low birth weight and moderately low birth weight multiplegestation infants was lower than for singletons in similar birth-weight categories. However, they did not evaluate ELBW infants separately.…”

Section: Discussionmentioning

confidence: 99%

“…Others also have shown similar trends of higher maternal age and greater use of prenatal care and prenatal steroids in mothers with multiple pregnancies compared with singleton pregnancies. 5 The reasons for these differences are not clear and may be related to multiple factors, including a higher use of artificial reproductive technologies in the triplet or higherorder multiple-birth population.…”

Section: Figurementioning

confidence: 99%

“…1 Previous data regarding survival and morbidities in extremely low birth weight (ELBW) multiple births have been scarce and conflicting. Although some studies 4 have shown that higherorder multiples are associated with a higher mortality rate compared with twins, others 5 have shown that the survival rate is better. We have previously shown that ELBW twins have a higher risk of death or neurodevelopmental handicap compared with singletons in the same birth-weight category.…”

mentioning

confidence: 98%

See 2 more Smart Citations

Neurodevelopmental Outcomes of Triplets or Higher-Order Extremely Low Birth Weight Infants

Wadhawan

Vohr

et al. 2011

Pediatrics

View full text Add to dashboard Cite

BACKGROUND: Extremely low birth weight twins have a higher rate of death or neurodevelopmental impairment than singletons. Higher-order extremely low birth weight multiple births may have an even higher rate of death or neurodevelopmental impairment. METHODS: Extremely low birth weight (birth weight 401–1000 g) multiple births born in participating centers of the Neonatal Research Network between 1996 and 2005 were assessed for death or neurodevelopmental impairment at 18 to 22 months' corrected age. Neurodevelopmental impairment was defined by the presence of 1 or more of the following: moderate to severe cerebral palsy; mental developmental index score or psychomotor developmental index score less than 70; severe bilateral deafness; or blindness. Infants who died within 12 hours of birth were excluded. Maternal and infant demographic and clinical variables were compared among singleton, twin, and triplet or higher-order infants. Logistic regression analysis was performed to establish the association between singletons, twins, and triplet or higher-order multiples and death or neurodevelopmental impairment, controlling for confounding variables that may affect death or neurodevelopmental impairment. RESULTS: Our cohort consisted of 8296 singleton, 2164 twin, and 521 triplet or higher-order infants. The risk of death or neurodevelopmental impairment was increased in triplets or higher-order multiples when compared with singletons (adjusted odds ratio: 1.7 [95% confidence interval: 1.29–2.24]), and there was a trend toward an increased risk when compared with twins (adjusted odds ratio: 1.27 [95% confidence: 0.95–1.71]). CONCLUSIONS: Triplet or higher-order births are associated with an increased risk of death or neurodevelopmental impairment at 18 to 22 months' corrected age when compared with extremely low birth weight singleton infants, and there was a trend toward an increased risk when compared with twins.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Figurementioning

confidence: 99%

mentioning

confidence: 98%

See 1 more Smart Citation

Neurodevelopmental Outcomes of Triplets or Higher-Order Extremely Low Birth Weight Infants

Wadhawan

Vohr

et al. 2011

Pediatrics

View full text Add to dashboard Cite

show abstract

“…Fetoscopic laser therapy of the communicating vessels has been shown to be safe, effective and superior to serial amniodrainage in twin pregnancies 2 . Because of the rarity of monochorionic and dichorionic triplets 3 , at present little is known about the feasibility and success rate of laser therapy for TTTS in triplets. However, triplet rates and especially the dizygotic triplet rate have been increasing recently.…”

Section: Introductionmentioning

confidence: 99%

Laser therapy of twin‐to‐twin transfusion syndrome in triplet pregnancies

Diemert

Diehl

Huber

et al. 2009

Ultrasound in Obstet & Gyne

View full text Add to dashboard Cite

show abstract

“…Seventy-two of these pregnancies (64%) concluded in live birth, 8 (7%) in second-or third-trimester intrauterine fetal death, and 32 (29%) in either therapeutic or spontaneous abortion. The rate of twin pregnancies was 5.4% (6/112), which is about five times higher than the 0.34-1.1% rate reported in Black and Caucasian pregnant women [9]. All twins were dizygotic.…”

Section: Resultsmentioning

confidence: 60%

Folate supplementation and twinning in patients with sickle cell disease

2006

View full text Add to dashboard Cite

Patients with sickle cell disease routinely take folic acid daily as a supplement to maintain effective erythropoiesis. One of the controversial effects of folic acid is its effect on twin gestation rates. In this report, we present our experience in patients with sickle cell disease and twin pregnancy. Our data show that twin pregnancies seem to be associated with folate supplementation. Am. J. Hematol. 81:296-297, 2006 V V C 2006 Wiley-Liss, Inc.

show abstract

The Changing Epidemiology of Multiple Births in the United States

Cited by 53 publications

References 5 publications

Neurodevelopmental Outcomes of Triplets or Higher-Order Extremely Low Birth Weight Infants

Neurodevelopmental Outcomes of Triplets or Higher-Order Extremely Low Birth Weight Infants

Laser therapy of twin‐to‐twin transfusion syndrome in triplet pregnancies

Folate supplementation and twinning in patients with sickle cell disease

Contact Info

Product

Resources

About