The changing pattern of lung cancer by histological type — a review of 1151 cases from a university hospital in Japan, 1970–1989

Ikeda, Togo; Kurita, Yukio; Inutsuka, Sadaaki; Tanaka, Kiyoko; Nakanishi, Yoichi; Shigematsu, Nobuaki; Nobutomo, Koichi

doi:10.1016/0169-5002(91)90074-g

Cited by 26 publications

(9 citation statements)

References 14 publications

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“…Ikeda et al, in a review of 1151 cases from a University hospital between 1970 and 1989 [15] reported that the proportion of ADLC increased from 26 to 45% in males and from 45 to 69% in females. However, some surveys have failed to show this change: a study from the Tumour Registry of New Mexico, USA, showed an increasing proportion of SCLC rather than ADLC among the female population, but a histological diagnosis was only available in half of the cases.…”

Section: Discussionmentioning

confidence: 99%

Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data

Kontakiotis

Manolakoglou

Zoglopitis

et al. 2016

Monaldi Arch Chest Dis

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Background and Aim. The relative frequency of histological subtypes of lung cancer in Europe has changed dramatically during the 20th century. The aim of this study was to explore the changing epidemiology of lung cancer in Northern Greece over the last two decades. Methods. From the extensive database of the Bronchoscopy Unit of the G. Papanicolaou General Hospital, Thessaloniki, Greece, we identified all patients with a histologic and/or cytologic report positive for lung cancer over two consecutive decades. Results. Between 1/1/1986 and 31/12/2005 we identified 9981 patients with specimens positive for lung cancer. A significant increase in mean patient age was observed during the second decade (64.8±9.4 vs. 62.1±8.9, p=0.001). Men developed lung cancer ten times more often than women. The predominant histological type was squamous cell cancer in males (4203 cases, 45.7%) and adenocarcinoma (418 cases, 52.6%) in females. The number of lung cancer cases was significantly higher during the second decade compared to the first decade (5766 cases [57.8%] vs. 4215 cases [42.2%], respectively, p<0.001). There was a significant decrease in the percentage of squamous cell carcinoma in males in the second decade (2317 cases [44.1%] vs. 1886 cases [48.0%], p<0.001), and an increase in adenocarcinoma (1021 cases [19.4%] vs. 609 [11.6%], p<0.001). In females, the relative incidence of adenocarcinoma was decreased and that of squamous cell carcinoma was increased, but not significantly. There was no obvious change in the incidence of small cell lung cancer. Neoplastic lesions were most often located in the upper lobes. Conclusion. The number of lung cancer cases has increased in the last decade. Squamous lung cancer appears to be decreasing in men and increasing in women. Adenocarcinoma appears to be increasing in men and decreasing in women. There appears to be no change in small cell lung cancer. During the second decade there has been a significant decrease in the male: female ratio.

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Section: Discussionmentioning

confidence: 99%

Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data

Kontakiotis

Manolakoglou

Zoglopitis

et al. 2016

Monaldi Arch Chest Dis

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“…22) There are also several reports on the trends of histologic types in Japan from hospital-based studies, 23,24) autopsy series [25][26][27] and a population-based registry.…”

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confidence: 99%

“…22) The distribution of histologic types in Japan shows a higher proportion of adenocarcinoma compared to that in European countries. 22) There are also several reports on the trends of histologic types in Japan from hospital-based studies, 23,24) autopsy series [25][26][27] and a population-based registry. 28) Most studies in Japan also showed a relative increase of adenocarcinoma and small cell carcinoma when compared to squamous cell carcinoma in both sexes.…”

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confidence: 99%

Trends of Lung Cancer Incidence by Histologic Type: A Population‐based Study in Osaka, Japan

Sobue

Ajiki

Tsukuma

et al. 1999

Japanese Journal of Cancer Research

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We investigated trends of lung cancer incidence from 1974 to 1993 by histologic type, using data from the population-based cancer registry in Osaka, Japan. Since the proportion of cases with histologic types identified was not sufficiently high, sex-and age-specific incidence rates by histologic types were estimated assuming that the distribution of histologic types was the same across the same sex and age group regardless of reporting status. Cumulative risk from 0 to 74 years old for total lung cancer increased 1.3-fold from the period 1974-77 to 1986-89 and then plateaued in the period 1990-93 for both males and females. When divided into histologic types, cumulative risk for incidence of squamous cell carcinoma was almost constant during the study period for both males and females. During the same period, adenocarcinoma increased up to 1.4-fold for both males and females. This increase seemed to have reached a plateau recently for males, but not for females. Small cell carcinoma increased monotonously up to 1.6-to 1.7-fold for both males and females. Large cell carcinoma showed over 2-fold increase for both males and females; however, the estimates fluctuated due to the small number of cases. This study provides further evidence of a relative increase of adenocarcinoma compared to squamous cell carcinoma. Recent trends of tapering increase of lung cancer incidence should be confirmed by further observation.Key words: Lung cancer -Histologic type -Incidence -Trend -Smoking Recent trends of lung cancer incidence are showing different patterns by country. 1) In the US and UK, where lung cancer incidences were relatively high and smoking control has been successfully implemented, incidence of lung cancer in males has reached a peak and now is in the decreasing phase, starting from younger age groups. In contrast, in Eastern Europe, where smoking control has been less successful, the incidence is still increasing. These trends have been greatly influenced by the trends of smoking prevalence. It is well known that the magnitude of association between lung cancer and cigarette smoking differs by histologic types. Squamous cell carcinoma and small cell carcinoma show a 10-to 20-fold increase among current smokers compared to non-smokers, while adenocarcinoma shows a 2-to 5-fold increase.2) Therefore, smoking prevalence influences the trends of incidences differently among histologic types.In the US and Europe, several hospital-based studies, [3][4][5][6] autopsy series 7) and population-based studies [8][9][10][11][12][13][14][15][16] have examined the trends of lung cancer incidence by histologic type. In Asian countries there have been hospitalbased studies, [17][18][19][20] and a population-based study. 21) Most of the studies showed a relative increase of adenocarcinoma as compared to squamous cell carcinoma in both males and females, especially in younger age groups. Lung cancer incidence in Japan has been relatively low compared to other countries. It is reported that cumulative risk (0-74 years old) of lung c...

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“…BARSKY et al [20] reported an increasing incidence of BAC, rising from <5 to 24% in successive 5 year periods from 1975 to 1990; much of this increase occurring in women [27,28]. BAC have a wide variety of radiological manifestations, ranging from a single solid or cavitated nodule to multilobar consolidations [21,22].…”

Section: Discussionmentioning

confidence: 99%

Bronchioloalveolar carcinoma: computed tomography findings

Trigaux¹,

Gevenois²,

Goncette³

et al. 1996

Eur Respir J

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The changing pattern of lung cancer by histological type — a review of 1151 cases from a university hospital in Japan, 1970–1989

Cited by 26 publications

References 14 publications

Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data

Epidemiologic trends in lung cancer over two decades in Northern Greece: an analysis of bronchoscopic data

Trends of Lung Cancer Incidence by Histologic Type: A Population‐based Study in Osaka, Japan

Bronchioloalveolar carcinoma: computed tomography findings

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