The circulating IL‐35+ regulatory B cells are associated with thyroid associated opthalmopathy
Qian Li,
Cuixia Yang,
Cheng Liu
et al.
Abstract:BackgroundThyroid‐associated ophthalmopathy (TAO) is the most common orbital disease in adults, potentially leading to disfigurement and visual impairment. However, the causes of TAO are not fully understood. IL‐35+B cells are a newly identified regulatory B cells (Bregs) in maintaining immune balance in various autoimmune diseases. Yet, the influence of IL‐35+Bregs in TAO remains unexplored.MethodsThis study enrolled 36 healthy individuals and 14 TAO patients. We isolated peripheral blood mononuclear cells an… Show more
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