The Clinical Intoxication Induced by a Heparinoid

Field, John; Attyah, Albert M.; Ramsay, G. D.; Levitt, Harry

doi:10.1097/00000441-196105000-00013

Cited by 10 publications

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“…It has been reported that GAG, particularly heparin, heparan sulfate and dermatan sulfate, have specific effects on the growth of hair in the whole animal (Field et al 1961 ;Meyer et al 1961). In cell culture, therefore, overproduction of particular GAG species or overgrowth by cells producing GAG could alter the differentiation of the remaining cells.…”

Section: Discussionmentioning

confidence: 99%

Production of GJycosaminoglycans by Rat Hair Follicle Cells in Vitro

Frater¹,

Hewish²

1981

Aust. Jnl. Of Bio. Sci.

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Aust. J. Bioi. Sci., 1981,34, 171-8 Cultures of cells from rat dermal tissue, containing a large proportion of cells from the hair follicles, were found to produce glycosaminoglycans. The glycans were associated with the cell aggregates which typically form in such cultures, and also appeared to be present in material which was released from the cells. Examination of the glycosaminoglycan species present in the cultures showed the presence of hyaluronic acid, dermatan sulfate, chondroitin-4-sulfate, heparin and heparan sulfate-C, the first two compounds being secreted.into the culture medium. The patterns of synthesis and sulfation of glycosaminoglycans were found to change with continued time in culture.

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Section: Discussionmentioning

confidence: 99%

Production of GJycosaminoglycans by Rat Hair Follicle Cells in Vitro

Frater¹,

Hewish²

1981

Aust. Jnl. Of Bio. Sci.

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“…The reported incidence of alopecia varies from 19% (Hirschboeck, Madison & Pisciotta, 1954) to 70% (Field et al, 1961). The response appears to be related to the highest dose given rather than to the duration of treatment (Tudhope, Cohen & Meikle, 1958;Hirschboeck et al, 1954).…”

Section: Anticoagulantsmentioning

confidence: 99%

Drug Reactions Xxiii.

Levantine

Almeyda²

1973

Br J Dermatol

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“…Numerous drugs have been implicated as causing alopecia by various means (1)(2)(3)(4)(5)(6)(7). There are some others which produce lichenoid eruptions (8).…”

Section: Introductionmentioning

confidence: 99%

Isonicotinic Acid Hydrazide Induced Anagen Effluvium and Associated Lichenoid Eruption

Sharma,

Gautam,

Bhardwaj

et al. 2001

The Journal of Dermatology

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A 32 year‐old woman developed generalised lichenoid eruptions on her body followed by diffuse loss of scalp hair of the anagen effluvium type. She was receiving several anti‐tubercular drugs, including rifampicin, isonicotinic acid hydrazide (INH), pyrazinamide, and ethambutol, for abdominal tuberculosis. INH, which is a leading cause of drug eruptions in the above group of drugs was withdrawn. However, the other antitubercular drugs were continued along with 40 mg of prednisolone in a single daily morning dose. The latter was discontinued slowly over a period of 10 weeks. There was complete recovery of hair loss and the regrowth started after 12 weeks of alopecia. Such anagen effluvium with lichenoid eruption following INH therapy has not been observed previously. The complete recovery from anagen effluvium is difficult to explain, but it could have been because of the early initiation of corticosteroid.

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The Clinical Intoxication Induced by a Heparinoid

Cited by 10 publications

References 0 publications

Production of GJycosaminoglycans by Rat Hair Follicle Cells in Vitro

Production of GJycosaminoglycans by Rat Hair Follicle Cells in Vitro

Drug Reactions Xxiii.

Isonicotinic Acid Hydrazide Induced Anagen Effluvium and Associated Lichenoid Eruption

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