The clinical involvement patterns of neuro‐Behçet's disease

Yücesan, Canan; Işıkay, Canan Togay; Özay, Emine; Aydın, Nimet Sermenli; Mutluer, Nermin

doi:10.1046/j.1468-1331.2001.00177.x

Cited by 7 publications

(3 citation statements)

References 7 publications

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“…Brainstem involvement has been most commonly reported in patients with parenchymal NBD, followed by hemispheric, basal ganglia, thalamus, and spinal cord involvement, which is compatible with our study ( 4 , 8 , 10 , 11 , 17 , 18 , 20 , 21 , 23 , 25 , 29 , 30 – 32 ). We found that hemispheric lesions were predominant in patients with severe NBD compared with mild-moderate NBD (p=0.006).…”

Section: Discussionsupporting

confidence: 92%

Clinical characteristics and prognosis of Neuro-Behçet’s disease

2018

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ObjectiveNeuro-Behçet’s disease (NBD) is a rare manifestation of Behçet’s disease (BD) and may cause severe disability. The aim of this study was to evaluate the treatment response in patients with NBD and to investigate the parameters that may influence the prognosis of the disease in patients with severe to mild-moderate disability.MethodsThe files of 60 patients admitted to our outpatient clinic for NBD between January 2007 and June 2014 were retrospectively reviewed. We compared the BD duration, time to NBD, NBD type and course, clinical findings of BD, functional neurological system involvement, localization of lesions on brain MRI, and all the medications between the severe and mild-moderate disability groups.ResultsThe mean time to the onset of NBD was significantly longer (17.8±4.6 years) and the mean age was significantly higher (50.25±9.1 years) in patients with severe disability than in those with mild-moderate disability (7.5±8.0 years and 37.5±10.9 years; p=0.01 and p=0.03, respectively). Moreover, hemispheric involvement was significantly associated with severe disability (p=0.006). No difference was found with regard toother investigated parameters between the groups.ConclusionWe believe that severe neurological disability may be associated with older age at the onset of NBD or longer time to NBD and hemispheric lesions on brain MRI. However, our results should be cautiously evaluated with further research.

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Section: Discussionsupporting

confidence: 92%

Clinical characteristics and prognosis of Neuro-Behçet’s disease

2018

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“…10 reported that 12.2% of NBD patients had CVT and the diagnosis of CVT was associated with favorable outcome. According to Yücesan et al, 11 two out of 39 patients with NBD had CVT, While Gökçay et al 12 identified that 15 out of 54 patients with NBD had CVT.…”

Section: Resultsmentioning

confidence: 99%

“…[2,9,[11][12][13][14][15][16][17]20,30,[34][35][36][37][38][39][40] Moreover, warfarin and acetyl salicylic acid have been given to some CVT patients with BD. [10][11][12]17,26,34 Wechsler et al 14 reported that treatment of CVT during acute phase consisted of combined heparin and steroids in 19 patients, steroids alone in three, and heparin alone in three others. Neurologic symptoms improved rapidly in all.…”

Section: Resultsmentioning

confidence: 99%

Cerebral Venous Thrombosis in Behçet's Disease Patients Compared to Other Causes of Cerebral Venous Thrombosis: a Retrospective Study

et al. 2016

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Objectives: This study aims to report the outcomes of patients with Behçet's disease (BD) with cerebral venous thrombosis (CVT) due to BD compared to patients with CVT due to other causes and to discuss the treatment options. Patients and methods: Files of 47 patients admitted to our outpatient clinic for CVT between January 2007 and November 2014 were retrospectively reviewed. Patients were divided into two groups; group 1 included 21 CVT patients with BD (9 males, 12 females; mean age 47±12 years; range 27 to 69 years) and group 2 included 26 CVT patients without BD (11 males, 15 females; mean age 45±16 years; range 25 to 79 years). We collected data for diagnosis for BD and CVT, duration of all medications, functional system involvement, baseline Expanded Disability Status Scale scores, modified Rankin Scale scores at follow-up, and localizations of lesions in brain magnetic resonance imaging and magnetic resonance venography. Results: Mean follow-up duration was four years in group 1 and two years in group 2. There was no significant difference between the groups regarding age, sex, neurological symptoms/findings and baseline Expanded Disability Status Scale scores. Localizations of occluded sinus in group 1 and group 2 were similar. For acute CVT, patients were treated with intravenous high dose prednisolone in group 1 and with anticoagulant in group 2. Follow-up modified Rankin Scale score was 0 in both groups. Conclusion: Our study revealed similar clinical and radiological findings in CVT patients with or without BD. Although medications used for treatment were different between the groups, treatment responses were good in both groups. Treatment with prednisolone may be sufficient and anticoagulation therapy may not be necessary for acute CVT attacks in BD.

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Manifestations neurologiques de la maladie de Behçet

Chentouf

Gourine

2022

Pratique Neurologique - FMC

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The clinical involvement patterns of neuro‐Behçet's disease

Cited by 7 publications

References 7 publications

Clinical characteristics and prognosis of Neuro-Behçet’s disease

Clinical characteristics and prognosis of Neuro-Behçet’s disease

Cerebral Venous Thrombosis in Behçet's Disease Patients Compared to Other Causes of Cerebral Venous Thrombosis: a Retrospective Study

Manifestations neurologiques de la maladie de Behçet

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