The Coexistence of Rathke Cleft Cyst and Pituitary Adenoma

Gao, Mingtong; An, Yanyan; Huang, Zhihong; Niu, Jianyi; Yuan, Xunhui; Bai, Yun′an; Guo, Liemei

doi:10.1097/scs.0000000000002371

Cited by 9 publications

(1 citation statement)

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“…"Subclinical pituitary apoplexy" is widely used to describe pathological evidence of asymptomatic pituitary ischemia or hemorrhage. 12,13 CONCLUSION This retrospective study established a baseline proÀle of CNS tumors and sellar lesions in the Southern Kerala This study has few limitations as a relatively small sample size restricted to one tertiary care private hospital. Given the high frequency of PA/Pituitary Neuroendocrine Tumours, their potential for causing clinical pathologies, the Àndings of the current study suggest that early diagnosis and treatment of PA should have far reaching beneÀts as they mainly affect the economically active population and are associated with increased morbidity and mortality.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2024

IJPRP

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Primary Central Nervous System tumors (CNS trs) are a diverse group of neoplasm showing significant geographic variations in incidence, morbidity, mortality, and survival. Pituitary adenomas (PA) recently termed as Pituitary Neuroendocrine Tumours (PitNET) are the commonest mass in the sellar region, can produce local, and distant effects. 1 However, some developmental, inflammatory, and neoplastic lesions may primarily or secondarily involve the sella, mimicking pituitary tumors; recognition of which is crucial for the appropriate management.Aims: To evaluate the histopathological profile of primary CNS trs and to correlate with age, sex and site at presentation. Pituitary lesions are further analyzed to find out prevalence of non adenomatous lesions in pituitary Materials and methods: Histologically diagnosed 79 primary CNS trs and 18 pituitary lesions are analyzed.Results: Meningioma is the commonest brain and CNS trs. The PA being the second commonest CNS trs, constitute 17% of CNS trs, 22% of brain tumors and 78% of pituitary lesions. Other sellar lesions were single cases of Rathkeys cleft cyst (RCC), Arachnoid cyst, craniopharyngioma and pituitary apoplexy. Conclusion:This retrospective study established a baseline profile of brain tumors and sellar lesions based primarily on the histopathological experience at a tertiary care hospital in the Southern Kerala.

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Section: Discussionmentioning

confidence: 99%

Untitled

2024

IJPRP

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“Intrasellar tumor-to-tumor metastasis: A single center experience with a systematic review”

Mansur,

Alsavaf,

Pasquini

et al. 2024

Pituitary

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Purpose This study investigates the rare occurrence of tumor-to-tumor metastasis in Pituitary Neuroendocrine Tumors (PitNETs), also known as pituitary adenomas, aiming to enhance understanding of its diagnostic and therapeutic challenges. We report two cases from our institution of tumor-to-tumor metastasis involving PitNETs, followed by a systematic literature review. Methods We conducted a comprehensive literature review using PubMed and Google Scholar databases. This review provides insights into patient demographics, clinical presentations, primary tumor origin, management approaches and outcomes. Results We identified 38 documented cases of tumor-to-tumor metastasis involving the pituitary gland in the literature. This revealed a diverse range of primary tumor origins, with lung, breast, and renal carcinomas being the most prevalent. Clinical presentations varied, with visual disturbances emerging as the most frequently reported symptom. Surgical interventions predominantly resulted in subtotal resection. Kaplan–Meier survival analysis demonstrated that endoscopic endonasal approaches (EEA) are associated with longer median survival times compared to other surgical methods. Conclusion Tumor-to-tumor metastasis to PitNETs must be considered in differential diagnoses of sellar masses. Prompt and accurate diagnosis, coupled with a multidisciplinary treatment strategy, is essential. Our study contributes to the scarce literature on such metastases, providing a foundation for further understanding of this complex pathological entity.

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