The combined enamel remineralization potential of arginine and fluoride toothpaste

Bijle, Mohammed Nadeem Ahmed; Ekambaram, Manikandan; Lo, Edward Chin Man; Yiu, Cynthia Kar Yung

doi:10.1016/j.jdent.2018.06.009

Cited by 55 publications

(58 citation statements)

References 21 publications

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“…These differences can be attributed to the different biomaterial product treatments since the enriched gelatin gel-film was a stationary application compared with our mechanical brushing treatments. This was also confirmed from the study on demineralized human dentin restored by new composite materials after complete immersion for 7 days, providing a highest penetration depth between 30 and 50 µm [8]. The proposed new method for estimating the penetration depth provides proper statistic acquisitions since it is based on the entire probed large area of 30 × 40 µm 2 .…”

Section: Discussionsupporting

confidence: 63%

“…This difference can be related to the high amount of silicate in the fabricated fluorine biomaterials, as shown in the EDS-spectra of Figure 2b-S,c-S. The high amount of silicon in the toothpaste has been considered to promote the formation of apatite crystasl, but only in a supersaturated solution of Ca 2+ and PO 4 3− ions and further the calcium-silicate biomaterial has the ability to release mineral ions [8,26].…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, the diffusion effect of new composite material through demineralized human dentin was analyzed by line scan EDS on rough surfaces [7]. On the other hand, other biomimetic mineralization studies on pathological permanent dental features were only focused on calculating the Ca/P ratio (EDS technique) on an average extensive micrometric area for determining the regeneration crystal of enamel caries-like lesion by arginine (Arg) in sodium fluoride (NaF) toothpaste [8]. Highly concentrated stannous fluoride (SnF 2 ) and NaF solutions and a NaF/CaF 2 varnish on adult treated enamel have been analyzed in terms of erosion and abrasion by scanning electron microscopy (surface morphology) and EDS microanalysis [9].…”

Section: Introductionmentioning

confidence: 99%

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Morpho-Chemical Observations of Human Deciduous Teeth Enamel in Response to Biomimetic Toothpastes Treatment

et al. 2020

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Today, biomaterial research on biomimetic mineralization strategies represents a new challenge in the prevention and cure of enamel mineral loss on delicate deciduous teeth. Distinctive assumptions about the origin, the growth, and the functionalization on the biomimetic materials have been recently proposed by scientific research studies in evaluating the different clinical aspects of treating the deciduous tooth. Therefore, appropriate morpho-chemical observations on delivering specific biomaterials to enamel teeth is the most important factor for controlling biomineralization processes. Detailed morpho-chemical investigations of the treated enamel layer using three commercial toothpastes (Biorepair, F1400, and F500) were performed through variable pressure scanning electron microscopy (VP-SEM) and energy dispersive X-ray spectroscopy (EDS) on deciduous teeth in their native state. A new microscopy methodology allowed us to determine the behaviors of silicate, phosphate, and calcium contents from the early stage, as commercially available toothpastes, to the final stage of delivered diffusion, occurring within the enamel layer together with their penetration depth properties. The reported results represent a valuable background towards full comprehension of the role of organic–inorganic biomaterials for developing a controlled biomimetic toothpaste in biofluid media.

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Section: Discussionsupporting

confidence: 63%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Morpho-Chemical Observations of Human Deciduous Teeth Enamel in Response to Biomimetic Toothpastes Treatment

et al. 2020

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“…In a study that examined the remineralisation potential of arginine (Arg) in NaF toothpaste, mineral density was evaluated with μCT. With the addition of 2% arginine to NaF toothpaste, the remineralisation of lesions similar to enamel caries was observed to significantly increase (78).…”

Section: Restorative Treatment Applicationsmentioning

confidence: 99%

The use of micro-computed tomography in dental applications

2019

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Together with developments in digital imaging systems, there has been increasing use of micro-computed tomography (μCT) in many areas, primarily in dentistry. As this method allows 3-dimensional images to be taken providing safe and high quality results, without damaging the samples being examined, it is often preferred. Consequently, it has become possible to record rapid progression in endodontic studies in particular and to research and easily compare several techniques. Furthermore, this method can be used in tissue engineering, forming data for FEM analysis, the growth and development of craniofacial bones, imaging bone structure, and in the evaluation of implants and surrounding bone in root tip surgery, to determine mineral concentration in the teeth and to measure the thickness of enamel. The aim of this review was to focus on the areas of use of μCT in dentistry and state the advantages. Key Words: Micro-computed tomography, X-ray micro-CT, dental application, three-dimensional imaging How to cite this article: Erpaçal B, Adıgüzel Ö, Cangül S. The use of micro-computed tomography in dental applications. Int Dent Res 2019;9(2):78-91. Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

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“…387 Similarly, an in vitro study in high-risk specimens indicated that daily use of 2% arginine in NaF toothpaste provided synergistic anticaries activity by demonstrating a significant remineralization effect. 388 Conversely, an in vivo study followed up 12 participants wearing acrylic resin appliances with embedded bovine enamel disks. Brushing with fluoride toothpaste was compared with brushing with arginine-enhanced fluoride toothpaste.…”

Section: Prebioticsmentioning

confidence: 99%

Annual review of selected scientific literature: A report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry

Cagna

Donovan

McKee³

et al. 2019

The Journal of Prosthetic Dentistry

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The combined enamel remineralization potential of arginine and fluoride toothpaste

Cited by 55 publications

References 21 publications

Morpho-Chemical Observations of Human Deciduous Teeth Enamel in Response to Biomimetic Toothpastes Treatment

Morpho-Chemical Observations of Human Deciduous Teeth Enamel in Response to Biomimetic Toothpastes Treatment

The use of micro-computed tomography in dental applications

Annual review of selected scientific literature: A report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry

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