2021
DOI: 10.18596/jotcsa.861808
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The Compound Specific Antibacterial Activities of Major Urolithins and Their Methyl Ethers

Abstract: The investigation of biological activities of natural products, particularly considering the secondary metabolites, continuously receives attention. Urolithins, the bioavailable metabolites of ellagitannins, were shown to possess enzyme inhibitor, antioxidant, and anti-inflammatory compounds in scientific studies conducted in the last two decades. Regarding the limited number of studies related to their antimicrobial activity, this study aimed to synthesize major urolithins (Urolithin A and B) concomitant to t… Show more

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Cited by 4 publications
(1 citation statement)
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“…They exhibit impressive medicinal properties like antioxidant, 3 anti-inflammatory, 4 anticancer, 5 and antimicrobial activities. 6 Besides urolithins, there are several medicinally important natural products that possess the dibenzopyran-6-one motif. For instance, itolide A 3 , isolated from the seeds of Itoa orientalis Hemsl., exhibits antifungal activity against Sclerotium rolfsii.…”
Section: Introductionmentioning
confidence: 99%
“…They exhibit impressive medicinal properties like antioxidant, 3 anti-inflammatory, 4 anticancer, 5 and antimicrobial activities. 6 Besides urolithins, there are several medicinally important natural products that possess the dibenzopyran-6-one motif. For instance, itolide A 3 , isolated from the seeds of Itoa orientalis Hemsl., exhibits antifungal activity against Sclerotium rolfsii.…”
Section: Introductionmentioning
confidence: 99%