2023
DOI: 10.1016/j.ijchp.2023.100372
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The contribution of the cingulate cortex: treating depressive symptoms in first-episode drug naïve schizophrenia

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Cited by 2 publications
(2 citation statements)
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“…Fourth, due to the heterogeneous combination of symptoms and the complexity of pathophysiology in schizophrenia, the actual drug mechanisms and individual differences in clinical practice remain unclear. For example, the effects of antipsychotic drugs on psychotic symptoms vary with sex, and baseline depressive symptoms ( Shen et al, 2023 ; Haack et al, 2009 ). Future research should consider the influence of patients' baseline characteristics and individual differences on the treatment outcomes.…”
Section: Discussionmentioning
confidence: 99%
“…Fourth, due to the heterogeneous combination of symptoms and the complexity of pathophysiology in schizophrenia, the actual drug mechanisms and individual differences in clinical practice remain unclear. For example, the effects of antipsychotic drugs on psychotic symptoms vary with sex, and baseline depressive symptoms ( Shen et al, 2023 ; Haack et al, 2009 ). Future research should consider the influence of patients' baseline characteristics and individual differences on the treatment outcomes.…”
Section: Discussionmentioning
confidence: 99%
“…Además, tales alteraciones también estarían presentes en la sustancia blanca (axonales) (Roiz-Santiáñez et al, 2010;De Bartolomeis et al, 2022;Ramirez-Mejía et al, 2023). Por otro lado, estudios funcionales muestran una conectividad alterada tanto en la ínsula como en la corteza cingulada anterior en esquizofrenia (Wilmsmeier, 2010;Henseler, Falkai & Gruber, 2009;Shen et al, 2023). Esto ha llevado a la idea…”
Section: Disfunción Insular Alteraciones Dopaminérgicas Y Saliencia A...unclassified