The Critically Poisoned Patient

Donovan, J. Ward; Burkhart, Keith; Brent, Jeffrey

doi:10.1007/978-3-319-17900-1_14

Cited by 3 publications

(2 citation statements)

References 77 publications

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“…Usually referred to as deadly nightshade, and in Turkey as the 'beautiful woman herb' (3). AB is a toxic plant composed of atropine, hyoscyamine, and scopolaminxe alkaloids; atropa belladonna (AB) is a poison everyone should be careful of as there are reported cases of intoxication (4)(5)(6), especially in children who may mistaken the plant for cherries or blueberries (4,7,8).…”

Section: Atropa Belladonamentioning

confidence: 99%

Belladonna Delirium: Introduction, Overview and Literature Review

I. Osman,

A. Abdalla,

Y. Hammad

et al. 2023

IJRP

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Section: Atropa Belladonamentioning

confidence: 99%

Belladonna Delirium: Introduction, Overview and Literature Review

I. Osman,

A. Abdalla,

Y. Hammad

et al. 2023

IJRP

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“…Hemodynamic management should be performed with intravenous fluids, followed by vasopressors (norepinephrine) in cases where hypotension is not treated. The presence of hypotension, acidemia, and creatinine elevation is correlated with high mortality; therefore, these disorders must be managed promptly (14), (15). The most important electrolyte disorder is hypocalcaemia, which must be properly determined and treated in these patients.…”

Section: Treatmentmentioning

confidence: 99%

Sodium fluoracetate's poisoning: A case report

Reyes¹,

Mejía²,

Gómez-González³

et al. 2020

Rev. Médica Risaralda

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Introduction: Sodium fluoroacetate, known as compound 1080, was discovered in Germany during the Second World War. It is usually used as a rodenticide, it is an odorless and tasteless substance, with a lethal dose in humans of 2 mg / kg that is why it was withdrawn from the market in some countries, including Colombia; however, it is obtained illegally. This substance has biochemical and physiological effects at the cellular level that alter the transport of citrate at the mitochondrial level, generating accumulation of lactic acid and alteration of the glucose use. The clinical manifestations are nonspecific since there is no any cardinal symptom. Therefore, its diagnosis is made due to high clinical suspicion associated with establishment of exposure to the compound in view of the difficulty to obtain paraclinical confirmation in a timely manner. Methods: We present a case report of intentional ingestion of sodium fluoroacetate in an adolescent that is associated with an infection added to the bloodstream by methicillin- sensitive Staphylococcus aureus (MSSA). The patient developed multiple complications that lead to support in the Intensive Care Unit (ICU) with a satisfactory outcome. In view of the lack of a specific antidote, she was treated with ethanol in order to increase the level of acetate; thus, offering an alternative substrate to the Krebs cycle. It is suggested that the ethanol offers benefits in the acute treatment of these patients. Results: The patient with sodium fluoroacetate poisoning and kidney failure received renal replacement therapy with a favorable evolution and survival at discharge from the intensive care unit of a third-level hospital in the city of Pereira, Risaralda, Colombia. Conclusions: Sodium fluoroacetate poisoning is relatively rare and can cause acute kidney injury and multi-organ failure with a high rate of complications and death. A case of self-inflicted poisoning that received a timely manner continuous renal replacement therapy with a favorable outcome in terms of ICU survival was presented.

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Intoxicaciones por sustancias químicas en población gestante, Colombia, 2013-2014

García¹,

Guerrero²

2016

Inf. epidemiol. nac

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Introducción: Las intoxicaciones por sustancias químicas durante el periodo de gestación constituyen un reto para el personal de salud por la potencial amenaza a la vida al binomio materno fetal y posibles complicaciones que se generan (1-3). El presente estudio retrospectivo describe el comportamiento de las intoxicaciones en gestantes ocurridas durante el 2013 y 2014 notificadas al Sistema de Vigilancia en Salud Pública (Sivigila) para priorizar acciones de intervención y prevención. Metodología: Se consolidó una base de casos calculando proporciones y medidas de tendencia central y dispersión según las variables. Se elaboraron tablas de frecuencia y calcularon las proporciones de incidencia del evento para ser representadas por departamento de procedencia. Resultados: Se reportaron 791 casos de intoxicaciones que corresponden al 1,3% del total de notificaciones. El 73,19 % ocurrió en gestantes jóvenes con escolaridad secundaria 58,4 %, predominando la intencionalidad suicida 75,72%y el estado civil soltero 45,1%. El grupo de sustancia que prevaleció fueron los plaguicidas 39,95 %. Conclusiones: Las intoxicaciones en gestantes, es un hallazgo con importantes implicaciones para la salud materno fetal a corto, mediano y largo plazo. El porcentaje de intoxicaciones intencionales sugiere la presencia de factores psicosociales que deben evaluarse durante el control prenatal para prevenir futuros eventos. Se debe priorizar el seguimiento del evento algunas zonas del país y realizar rutinariamente una prueba de embarazo a toda mujer en edad fértil con sospecha de intoxicación con intención suicida, ya que sus resultados pueden modificar la conducta y pronóstico para la madre y el feto.

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The Critically Poisoned Patient

Cited by 3 publications

References 77 publications

Belladonna Delirium: Introduction, Overview and Literature Review

Belladonna Delirium: Introduction, Overview and Literature Review

Sodium fluoracetate's poisoning: A case report

Intoxicaciones por sustancias químicas en población gestante, Colombia, 2013-2014

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