The Cytological Diagnosis of Endometrial Pathology Using a Uterine Aspiration Technique

Wachtel, E; Gordon, H.; Wycherley, J.

doi:10.1111/j.1471-0528.1973.tb02174.x

Cited by 9 publications

(1 citation statement)

References 2 publications

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“…One missed carcinoma is not uncommon in reports of other endometrial screening techniques (Wachtel et al, 1973;Isaacs and Ross, 1978;Studd et al, 1979), but the low rate of detection of other endometrial lesions (Table 4) and the evidence that sampling of the endometrial cavity was sometimes incomplete are unsatisfactory.…”

Section: Discussionmentioning

confidence: 99%

An assessment of the Mi-Mark endoemtrial sampling technique.

Crow¹,

Gordon²,

Hudson³

1980

J Clin Pathol

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SUMMARY One hundred and twenty cytological smears and 106 histological specimens were obtained from 115 patients using a new technique of endometrial sampling. It proved an atraumatic procedure and was well accepted by the patients. Some problems were encountered in the preparation of satisfactory cytological specimens and in their interpretation. The method was not completely reliable for detecting endometrial pathology and is therefore considered unsuitable for monitoring patients on hormone replacement therapy. It was found to be useful as a gynaecological outpatient technique for sampling the endometrium when formal curettage was unsuccessful, in avoiding the necessity for a preoperative curettage to confirm suspected carcinoma, and in the investigation of infertility.

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Section: Discussionmentioning

confidence: 99%

An assessment of the Mi-Mark endoemtrial sampling technique.

Crow¹,

Gordon²,

Hudson³

1980

J Clin Pathol

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The value of endometrial cytology by scraping in 1, 798 cases: Screening in asymptomatic women and diagnosis in symptomatic ones

Porrazzi

Quarto

Maiello

et al. 1987

Diagnostic Cytopathology

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A study of 1,798 endometrial cytological samples, obtained with an "endocyte" (a disposable scraping device) and controlled in histology is presented. The method was tested for its usefulness in screening of precancerous lesions and preclinical cancer in 1,248 asymptomatic women and in the diagnosis of endometrial pathology in 550 symptomatic ones. The classification of hyperplasia into benign simplex and complex hyperplasia and atypical hyperplasia was followed; atypical hyperplasia, considered real intraepithelial neoplasia, was included in the positive cases. Histological verification was made chiefly on cell block in asymptomatic cytologically negative cases and either on curettage or hysterectomies in the others. The main endometrial cytological patterns are described. On the basis of findings, considering also endocyte's low cost, effectiveness, and ease of use, we think the method could be usefully employed in screening of endometrial cancer for an asymptomatic population. In symptomatic women, the use of histologic procedures is still preferable, and cytology cannot be considered a "first option" method.

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Endometrial cytology: Six years of experience

Mencaglia

1987

Diagnostic Cytopathology

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This article deals with a 6-yr mass screening program for the early detection of endometrial cancer, which took place 1978-1983. The diagnostic accuracy of endometrial cytology and the possibility of integrating this technique with the hysteroscopy and endometrial biopsy were studied. The authors analyzed 2,504 outpatients, all over the age of 45. The results of endometrial cytology were compared with those found using hysteroscopy and endometrial biopsy. Endometrial cytology showed high sensitivity in diagnosing endometrial cancer (97.7%) and high specificity in diagnosing true negatives. However, this technique was not adequate in identifying benign endometrial pathology, e.g., endometrial hyperplasia, polyps, or submucous fibromas. Epidemiological and clinical data in our series were fundamental in establishing mass screening for the early detection of endometrial cancer using integrated techniques. These data should be taken into consideration for creating new projects. The significantly high prevalence of endometrial neoplasia even in asymptomatic women over 45 years of age (4 per 1000) and the possibility of improving the accuracy of endometrial diagnosis using hysteroscopy and endometrial biopsy were the cornerstones of this project.

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The Cytological Diagnosis of Endometrial Pathology Using a Uterine Aspiration Technique

Cited by 9 publications

References 2 publications

An assessment of the Mi-Mark endoemtrial sampling technique.

An assessment of the Mi-Mark endoemtrial sampling technique.

The value of endometrial cytology by scraping in 1, 798 cases: Screening in asymptomatic women and diagnosis in symptomatic ones

Endometrial cytology: Six years of experience

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