The cytotoxicity and antimicrobial efficiency of<i>Moringa oleifera</i>seeds extracts

Ali, Gamila H.; El‐Taweel, Gamila E.; ., M. Abbas Ali

doi:10.1080/0020723042000189877

Cited by 39 publications

(25 citation statements)

References 11 publications

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“…Inasmuch as M. oleifera seed extract exerts bactericidal activity in vitro against Gram-positive and Gram-negative bacteria (Cáceres et al 1991; Ali et al 2004; Oludoro and Aderiye 2007; Suarez et al 2003, 2005) and cyanobacteria are Gram-negative (Stanier and Cohen-Bazire 1977), we hypothesize that Moringa seed extracts have an antimicrobial activity against the cyanobacterium M. aeruginosa .…”

Section: Introductionmentioning

confidence: 88%

Anti-cyanobacterial activity of Moringa oleifera seeds

Lürling

Beekman

2009

J Appl Phycol

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Filtrates from crushed Moringa oleifera seeds were tested for their effects on growth and Photosystem II efficiency of the common bloom-forming cyanobacterium Microcystis aeruginosa. M. aeruginosa populations exhibited good growth in controls and treatments with 4- and 8-mg crushed Moringa seeds per liter, having similar growth rates of 0.50 (±0.01) per day. In exposures of 20- to 160-mg crushed Moringa seeds L−1, growth rates were negative and on average −0.23 (±0.05) .day−1. Presumably, in the higher doses of 20- to 160-mg crushed seeds per liter, the cyanobacteria died, which was supported by a rapid drop in the Photosystem II efficiency (ΦPSII), while the ΦPSII was high and unaffected in 0, 4, and 8 mg L−1. High-density populations of M. aeruginosa (chlorophyll-a concentrations of ∼270 µg L−1) were reduced to very low levels within 2 weeks of exposure to ≥80-mg crushed seeds per liter. At the highest dosage of 160 mg L−1, the ΦPSII dropped to zero rapidly and remained nil during the course of the experiment (14 days). Hence, under laboratory conditions, a complete wipeout of the bloom could be achieved. This is the first study that yielded evidence for cyanobactericidal activity of filtrate from crushed Moringa seeds, suggesting that Moringa seed extracts might have a potential as an effect-oriented measure lessening cyanobacterial nuisance.

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Section: Introductionmentioning

confidence: 88%

Anti-cyanobacterial activity of Moringa oleifera seeds

Lürling

Beekman

2009

J Appl Phycol

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“…Its plant parts are rich in flavonoids, tannins, saponins, terpenoids, proanthocyanadins, and cardiac glycosides (Vinoth et al 2012). M. oleifera seeds have been studied for their anti-microbial, anti-tumor, anti-inflammatory, antispasmodic, and diuretic properties (Cárceres et al 1992;Guevara et al 1999;Bharali et al 2003;Ali et al 2004;Chuang et al 2007).…”

Section: Methodsmentioning

confidence: 99%

Green-synthesized silver nanoparticles as a novel control tool against dengue virus (DEN-2) and its primary vector Aedes aegypti

et al. 2015

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Dengue is an arthropod-borne viral infection mainly vectored through the bite of Aedes mosquitoes. Recently, its transmission has strongly increased in urban and semi-urban areas of tropical and sub-tropical regions worldwide, becoming a major international public health concern. There is no specific treatment for dengue. Its prevention and control solely depends on effective vector control measures. In this study, we proposed the green-synthesis of silver nanoparticles (AgNP) as a novel and effective tool against the dengue serotype DEN-2 and its major vector Aedes aegypti. AgNP were synthesized using the Moringa oleifera seed extract as reducing and stabilizing agent. AgNP were characterized using a variety of biophysical methods including UV-vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and sorted for size categories. AgNP showed in vitro antiviral activity against DEN-2 infecting vero cells. Viral titer was 7 log10 TCID50/ml in control (AgNP-free), while it dropped to 3.2 log10 TCID50/ml after a single treatment with 20 μl/ml of AgNP. After 6 h, DEN-2 yield was 5.8 log10 PFU/ml in the control, while it was 1.4 log10 PFU/ml post-treatment with AgNP (20 μl/ml). AgNP were highly effective against the dengue vector A. aegypti, with LC50 values ranging from 10.24 ppm (I instar larvae) to 21.17 ppm (pupae). Overall, this research highlighted the concrete potential of green-synthesized AgNP in the fight against dengue and its primary vector A. aegypti. Further research on structure-activity relationships of AgNP against other dengue serotypes is urgently required.

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“…However, there is a fear that aluminum may induce Alzheimer's disease and strong carcinogenic properties (Crapper et al, 1973, Malleavialle et al, 1984. On the other hand, there is evidence that the use of extracts from plant species possessing both coagulating and antimicrobial properties are safe for human health (Muyibi &Okuofu, 1995;Okuda et al, 2000;Ali et al,2004;Akinnibosun et al, 2008Akinnibosun et al, & 2009.…”

Section: Introductionmentioning

confidence: 99%

Synergy Between Moringa oleifera Seed Powder And Alum In The Purification of Domestic Water

Dalen¹,

Pam²,

Izang³

et al. 2010

Science World Journal

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Moringa oleifera seeds were analyzed for chemical composition. Phytochemical screening indicates the presence of saponnins (+(+)), flavonoids (+(-))and alkaloids(+(-)).Insrumental analysis showed also the presence of sodium(15.21+0.10ppm),aluminum (12.210.012) potassium (14.210.013ppm) and sulphate (1.720.011 ppm). Similarly, commercial alum was also analyzed and the results showed the presence of sodium (10.470.1500), aluminum (18.170.024ppm), potassium (8.010.012ppm) and sulphate (3.730.010ppm). Jar test trials on raw water samples displayed favourably characteristics at 60% alum to 40% m.oleifera mg/l blend with total coliform count of 30ml -1 and turbidity of 3.2NTU below the WHO maximum permissible limit of 5NTU. Other parameters determined also showed conformity with WHO standards for drinking water. The results indicate that moringa oleifera has a double advantage compared to commercial alum because of the presence of phytochemicals which have been reported to possess antimicrobial properties with potentials for conjunctive use with alum for water purification in rural communities.

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The cytotoxicity and antimicrobial efficiency ofMoringa oleiferaseeds extracts

Cited by 39 publications

References 11 publications

Anti-cyanobacterial activity of Moringa oleifera seeds

Anti-cyanobacterial activity of Moringa oleifera seeds

Green-synthesized silver nanoparticles as a novel control tool against dengue virus (DEN-2) and its primary vector Aedes aegypti

Synergy Between Moringa oleifera Seed Powder And Alum In The Purification of Domestic Water

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