Information systems (IS) are nowadays at the core of many personal and institutional activities and influence daily life more than ever before. To understand, evaluate and envision the forms of how we interact with IS, interdisciplinary and multifaceted research efforts are required. At the Information and Market Engineering chair at the Karlsruhe Institute of Technology, this task is taken head-on via research that stretches from user experiences to system design. In this review, the present research foci at the department are outlined, together with a brief description of its origins and the global developments that underly the necessity of conducting these particular IS studies.