Abstract. With the development of science and technology, the study of the philosophy of science also has been subjected to the value more and more. Therefore, more and more philosophy of science resources are demanded, how to allow students to receive more abundant philosophy of science resources and increase students' self-learning ability desiderate to be solved in the field of philosophy of science. Database design in this paper is the groundwork for developing resource transmission system. First, the basic principles of database design were outlined; then, conceptual structure design was conducted. Among them, using E-R diagram to describe relations between entities; finally, logical structure design was carried on, which designed the structure of tables of teacher, student and philosophy of science resource. Contents of this paper have great significance to improve the effectiveness and efficiency of classroom teaching.