The Deflux experience in Canada generates both optimism and queries

Endoscopic Treatment of Vesicoureteral Reflux in Children with Dextranomer/Hyaluronic Acid—A Single Surgeon's 6-Year Experience

“…In addition, approximate 5% (12/239) was downgraded to grade I, and no further treatment was needed. These results are acceptable when we compare the cure rate obtained by other series shown in Table 2 or by open surgery, especially if we take into account the noninvasive nature of the technique [1, 5, 16]. Endoscopic treatment of high grade VUR has been evaluated in some series, and success rates vary from 55% to 90% [1].…”

“…The technique comprises a hydrodistention-implantation technique with subureteric or intraureteric transurethral injection of Deflux with a Fr. 9.5 pediatric cystoscope, which is the same as the technique described in the literatures until we obtained a “bulge” with an elevated, inverted crescent shape of the orifice [ 4 , 16 ]. Patients were maintained on their antibiotic prophylaxis until reflux was documented to be absent on postoperative VCUG or radionuclide cystogram at 3 months after injection.…”