In this paper, we present an investigation into plasma density disturbances and electric field perturbations associated with China, Sichuan, Wenchuan earthquake of magnitude M = 7.9 that occurred on May 12, 2008, at 06:28:01 UTC. The DEMETER (Detection of Electromagnetic Emissions Transmitted from Earthquake Regions) satellite was launched on June 29, 2004. The orbit of DEMETER is polar, circular with an altitude of 710 km and its main scientific objective is the study of ionospheric perturbations linked to seismic activity. For satellite orbits near the epicenter region, some ionospheric effects are investigated, which can be considered as possible earthquake precursors. The paper discusses anomalous effects in the ionosphere associated with the Wenchuan earthquake, which cannot be explained by factors of solar-magnetospheric origin. For satellite orbits eight to four days before the main shock, fluctuations in ion density and increase in horizontal and vertical components of electric field are observed near the epicenter. Posteffect is observed too. The observations suggest a coupling between the lithosphereatmosphere-ionosphere and can be associated with the earthquake growing processes in the lithosphere and troposphere zones above the source. The results of ionospheric anomalous effects are presented and discussed. The results obtained are important because they are observed very near to epicenter.