The dental amalgam issue. A review

Hanson, Michele A.; Pleva, J.

doi:10.1007/bf02041243

Cited by 45 publications

(12 citation statements)

References 60 publications

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“…In the rest of the globe amalgam remains popular because it is strong, durable, and relatively inexpensive. It is considered a safe material but despite this concerns over its use remain because of the continuous low-level release of mercury, a substance which is known to be toxic [4–8]. Summaries of some selected research reports concerning amalgam fillings can be found at http://www.yourhealthbase.com/amalgams.html.…”

Section: Dental Amalgammentioning

confidence: 99%

Oral Lichenoid Contact Lesions to Mercury and Dental Amalgam—A Review

McParland

Warnakulasuriya

2012

Journal of Biomedicine and Biotechnology

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Human oral mucosa is subjected to many noxious stimuli. One of these substances, in those who have restorations, is dental amalgam which contains mercury. This paper focuses on the local toxic effects of amalgam and mercury from dental restorations. Components of amalgam may, in rare instances, cause local side effects or allergic reactions referred to as oral lichenoid lesions (OLLs). OLLs to amalgams are recognised as hypersensitivity reactions to low-level mercury exposure. The use of patch testing to identify those susceptible from OLL is explored, and recommendations for removing amalgam fillings, when indicated are outlined. We conclude that evidence does not show that exposure to mercury from amalgam restorations poses a serious health risk in humans, except for an exceedingly small number of hypersensitivity reactions that are discussed.

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Section: Dental Amalgammentioning

confidence: 99%

Oral Lichenoid Contact Lesions to Mercury and Dental Amalgam—A Review

McParland

Warnakulasuriya

2012

Journal of Biomedicine and Biotechnology

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“…For several years there has been an intense discussion about possible adverse effects of metals released from dental mercury amalgams (1)(2)(3)(4)(5)(6)(7)(8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

Metal Exposure from Amalgam Alters the Distribution of Trace Elements in Blood Cells and Plasma

Lindh

Carlmark²,

Grönquist³

et al. 2001

Clinical Chemistry and Laboratory Medicine

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Twenty-seven consecutive patients with health problems associated with dental amalgam were recruited. In spite of thorough medical examinations, there were no diagnoses available. The patient group was dominated by women. A healthy age- and sex-matched control group with dental amalgams without symptoms was also recruited. Metal level monitoring in plasma and nuclear microscopy of isolated individual blood cells were carried out. Significant increases of copper, iron, zinc and strontium were found in patient plasma. There was no significant difference in plasma selenium between the groups. Mercury was significantly increased in patient plasma, although there was overlap between the groups. In erythrocytes a significant increase in calcium and a significant decrease in magnesium, copper, manganese and zinc were found. Calcium, magnesium, manganese and copper increased in patient neutrophil granulocytes. A significant decrease was found for zinc. A conspicuous finding was the presence of measurable mercury in a few of the cells from the patient but not in the control group. Thus, nuclear microscopy of isolated individual blood cells might provide a better diagnostic tool for metal exposure than blood plasma measurements.

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“…A similar survey of dentists found that although 89% of respondents believed that amalgams posed no risk, 52% reported that they would replace such restorations at a patient's request (Gerbert et al 1992). Reviews in both the scientific and lay literature link amalgam restorations to severe psychiatric, neurologic, and immunologic effects (Anonymous 1991;Fung and Molvar 1992;Hanson and Pleva 1991;Weiner et al 1990).…”

mentioning

confidence: 99%

Mercury derived from dental amalgams and neuropsychologic function.

Factor-Litvak

Hasselgren

Jacobs

et al. 2003

Environ Health Perspect

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There is widespread concern regarding the safety of silver-mercury amalgam dental restorations, yet little evidence to support their harm or safety. We examined whether mercury dental amalgams are adversely associated with cognitive functioning in a cross-sectional sample of healthy working adults. We studied 550 adults, 30-49 years of age, who were not occupationally exposed to mercury. Participants were representative of employees at a major urban medical center. Each participant underwent a neuropsychologic test battery, a structured questionnaire, a modified dental examination, and collection of blood and urine samples. Mercury exposure was assessed using a) urinary mercury concentration (UHg); b) the total number of amalgam surfaces; and c) the number of occlusal amalgam surfaces. Linear regression analysis was used to estimate associations between each marker of mercury exposure and each neuropsychologic test, adjusting for potential confounding variables. Exposure levels were relatively low. The mean UHg was 1.7 µg/g creatinine (range, 0.09-17.8); the mean total number of amalgam surfaces was 10.6 (range, 0-46) and the mean number of occlusal amalgam surfaces was 6.1 (range, 0-19). No measure of exposure was significantly associated with the scores on any neuropsychologic test in analyses that adjusted for the sampling design and other covariates. In a sample of healthy working adults, mercury exposure derived from dental amalgam restorations was not associated with any detectable deficits in cognitive or fine motor functioning.

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The dental amalgam issue. A review

Cited by 45 publications

References 60 publications

Oral Lichenoid Contact Lesions to Mercury and Dental Amalgam—A Review

Oral Lichenoid Contact Lesions to Mercury and Dental Amalgam—A Review

Metal Exposure from Amalgam Alters the Distribution of Trace Elements in Blood Cells and Plasma

Mercury derived from dental amalgams and neuropsychologic function.

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