The detection of stage I ovarian cancer by three-dimensional sonography and power Doppler

Kurjak, Asım; Kupešić, Sanja; Šparac, Vladimir; Prka, Matija; Bekavac, Ivanka

doi:10.1016/s0090-8258(03)00205-1

Cited by 57 publications

(26 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Kurjak et al found that the addition of 3D power Doppler to ultrasound morphology increased sensitivity and specificity to 97%À99%. With 3D morphology and power Doppler, 42/43 stage I ovarian cancers were detected in their study [31]. Although promising, ongoing screening trials using the above techniques in combination with the CA-125 tumor marker have not proven efficacious in diagnosing ovarian cancer at an early stage in the general population.…”

Section: Ovarian Cancermentioning

confidence: 99%

Angiogenesis in normal and neoplastic ovaries

et al. 2005

View full text Add to dashboard Cite

Ovarian physiology is intricately connected to hormonally regulated angiogenic response. Recent advances in the post genomic revolution have significantly impacted our understanding of ovarian function. In an angiogenesis perspective, the ovary offers a unique opportunity to unravel the molecular orchestration of blood vessel development and regression under normal conditions. A majority of ovarian cancers develop from the single layer of epithelium surrounding the ovaries. Angiogenesis is critical for the development of ovarian cancer and its peritoneal dissemination. The present review summarizes recent findings on the angiogenic response in neoplastic ovaries and discusses the prospects of using anti-angiogenic approaches to treat ovarian cancer.

show abstract

Section: Ovarian Cancermentioning

confidence: 99%

Angiogenesis in normal and neoplastic ovaries

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Recently, 3-D imaging has become available commercially and definitely has useful clinical applications in obstetrics, although the usefulness of 3-D images in gynecological diagnosis is still somewhat controversial. However, the clinical application of 3-D in the gynecologic field has advanced, especially as recently it has been reported [3][4] that 3-D images were useful in differentiating malignant from benign ovarian tumors.…”

Section: Discussionmentioning

confidence: 99%

MR and Ultrasound Imaging of Floating Globules in Mature Ovarian Cystic Teratoma

Umesaki

Nagamatsu²,

Yada

et al. 2004

Gynecol Obstet Invest

View full text Add to dashboard Cite

A rarely reported case of cystic teratoma with floating globules or fat balls is presented. Comparative imaging investigations of the floating globules in an ovarian cystic teratoma were performed using magnetic resonance and two- and three-dimensional ultrasound. Ultrasound imaging easily detected the floating globules, especially the 3-dimensional features showed almost the same findings that were observed macroscopically after surgery. Magnetic resonance thus clearly revealed the character of floating globules.

show abstract

“…82 A five-year retrospective analysis was performed on the data from 43 referred patients with suspected stage I ovarian cancer subsequently confirmed by histopathologist. All the patients were preoperatively evaluated by four complementary sonographic methods: 2D transvaginal gray-scale, 2D transvaginal color Doppler, 3D ultrasound and 3D power Doppler, during the week prior to surgery.…”

Section: Detection Of Stage I Diseasementioning

confidence: 99%

Screening for Ovarian Cancer: The Possible Improvement by 3D Ultrasound and 3D Power Doppler

Prka¹,

Honemeyer²

2010

Donald School Journal of Ultrasound in Obstetrics and Gynecology

Self Cite

View full text Add to dashboard Cite

In developed countries more women die annually from ovarian cancer than from all other gynecologic malignancies combined. The fact that the ovaries are deep within the pelvic cavity and difficult to palpate is an obstacle to early diagnosis, especially in peri-post menopausal women, the group with the highest incidence of the disease. Seventy percent of patients are not diagnosed with the disease until the cancer has metastasized beyond the ovaries and is at stage 3 or 4. Patients with stage 3 or 4 have a 5-year survival rate of only 20-30%. Given the burden of suffering associated with ovarian cancer and the clear survival gradient related to the stage of disease at diagnosis, there is great need for development of effective screening methods for early detection of epithelial ovarian cancer. Better understanding of ovarian cancer etiology and increasing knowledge of tumor biology have both contributed to identify efficient Serum Tumor Markers, to screen high-risk populations. Technical advances in the field of ultrasound made transvaginal sonography (TVS) become the most important diagnostic tool, and multimodal (Serum markers plus TVS) screening appears to be a diagnostic break-through in fighting ovarian cancer. Five case reports illustrate that new ultrasound technologies such as 3D volume acquisition and 3D power Doppler imaging promise more reliable identification of an abnormal ovarian tumor vascularity and tumor-typical vascular architecture, thus facilitating early stage 1 -detection of the disease.

show abstract

The detection of stage I ovarian cancer by three-dimensional sonography and power Doppler

Cited by 57 publications

References 25 publications

Angiogenesis in normal and neoplastic ovaries

Angiogenesis in normal and neoplastic ovaries

MR and Ultrasound Imaging of Floating Globules in Mature Ovarian Cystic Teratoma

Screening for Ovarian Cancer: The Possible Improvement by 3D Ultrasound and 3D Power Doppler

Contact Info

Product

Resources

About