The DIAGNOSTIC AND CLINICAL VALUE OF DETERMINATION OF Α1-Antitrypsin PHENOTYPE IN SYSTEMIC VASCULITIDES

The article summarizes the modern concepts of microscopic polyangiitis (MPA), a primary ANCA-associated systemic necrotizing vasculitis without immune globulin deposition (pauci-immune) that affects mainly small vessels, while granulomatous inflammation is absent. Necrotizing glomerulonephritis is very common and pulmonary capillaritis often occurs. MPA can cause rapidly progressive damage to organ systems. The modern possibilities of MPA treatment, primarily anti-B cell therapy with rituximab, are discussed.

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Microscopic polyangiitis: Modern concepts and treatment options

Муркамилов

Айтбаев²,

Фомин

et al. 2021

Naučno-praktičeskaâ revmatologiâ

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The DIAGNOSTIC AND CLINICAL VALUE OF DETERMINATION OF Α1-Antitrypsin PHENOTYPE IN SYSTEMIC VASCULITIDES

Cited by 1 publication

References 15 publications

Microscopic polyangiitis: Modern concepts and treatment options

Microscopic polyangiitis: Modern concepts and treatment options

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