The dual relationship between polypharmacy and frailty in nursing home residents: polypharmacy as a cause or a consequence?

Giardino, Federica; Landi, Gelsomina; Arcopinto, Michele; Cittadini, Antonio; Marra, Alberto M.

doi:10.1007/s11739-021-02885-8

Cited by 1 publication

(3 citation statements)

References 9 publications

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“…Palmer and colleagues29 determined that 47% of prefrail and 59% of frail older adults experience polypharmacy. Significantly, the prevalence of polypharmacy is as high as 86.4% for individuals in the skilled nursing and long-term care environment, with an average of 8.5 medications per person 30. Polypharmacy may be one of the reasons adults living in a facility setting were “twice as likely to be frail.”14…”

Section: Fried's Phenotypementioning

confidence: 99%

“…Significantly, the prevalence of polypharmacy is as high as 86.4% for individuals in the skilled nursing and long-term care environment, with an average of 8.5 medications per person. 30 Polypharmacy may be one of the reasons adults living in a facility setting were "twice as likely to be frail." 14 The significance of polypharmacy is its positive correlation with frailty and all-cause mortality.…”

Section: Polypharmacymentioning

confidence: 99%

“…However, many older adults report difficulties with sleep latency, sleep fragmentation, or altered sleep duration. The evidence states that sleep disturbances affect 9% to 50% of older adults throughout the world 22,33–35. It has been found that a bidirectional relationship exists between sleep impairments and frailty.…”

Section: Fried's Phenotypementioning

confidence: 99%

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Physical Therapist Management of a Person With Frailty Across the Continuum

Cabrera

2023

Topics in Geriatric Rehabilitation

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Management of the older adult with frailty is challenging. Multiple morbidities and their interrelationships can make the management of frailty arduous to diagnose and effectively treat. However, explicitly assessing for frailty can help optimize the older adult's care and provide an appropriate focus for the interventions. Effective treatment interventions must be individualized to encourage active participation and engagement. Appropriate dosing of exercise is essential. Nonetheless, the key to reversing or preventing a downward trajectory is increasing physical activity, necessitating the individual's active participation and empowerment.

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Section: Fried's Phenotypementioning

confidence: 99%

Section: Polypharmacymentioning

confidence: 99%