The dynamic consequences of amygdala damage on threat processing in Urbach–Wiethe Disease. A commentary on Pishnamazi et al. (2016)

Hortensius, Ruud; Terburg, David; Morgan, Barak; Stein, Dan J.; Honk, Jack van; Gelder, Béatrice de

doi:10.1016/j.cortex.2016.07.013

Cited by 13 publications

(5 citation statements)

References 64 publications

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“…The amygdala plays a role in affective stimulus perception also when the images are whole body expressions (Hadjikhani and De Gelder, 2003). However, its exact role is still a matter of debate as it may depend on factors like stimulus visibility (Pessoa et al, 2006), task (Pichon et al, 2012), and the intactness of amygdala (Hortensius et al, 2017). Similarly, Padmala et al (2010) showed a correlation between pulvinar responses and stimulus detection, especially for affective conditions.…”

Section: Multiple Areas Of Body Selectivitymentioning

confidence: 99%

A large-scale brain network of species-specific dynamic human body perception

Solanas

Marrazzo

et al. 2023

Progress in Neurobiology

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Section: Multiple Areas Of Body Selectivitymentioning

confidence: 99%

A large-scale brain network of species-specific dynamic human body perception

Solanas

Marrazzo

et al. 2023

Progress in Neurobiology

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“…We note, however, that patients treated with amygdalotomy were often cognitively impaired and nonverbal prior to surgery. Tests to assess other emotional and cognitive aspects (ie, threat processing, avoidance, and approach) 103,104 were usually not performed. Nevertheless, in most cases, authors reported transient or no postoperative side effects and no impairment in overall measures of intelligence and global memory.…”

Section: Amygdalamentioning

confidence: 99%

Amygdala and Hypothalamus: Historical Overview With Focus on Aggression

et al. 2019

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Aggressiveness has a high prevalence in psychiatric patients and is a major health problem. Two brain areas involved in the neural network of aggressive behavior are the amygdala and the hypothalamus. While pharmacological treatments are effective in most patients, some do not properly respond to conventional therapies and are considered medically refractory. In this population, surgical procedures (ie, stereotactic lesions and deep brain stimulation) have been performed in an attempt to improve symptomatology and quality of life. Clinical results obtained after surgery are difficult to interpret, and the mechanisms responsible for postoperative reductions in aggressive behavior are unknown. We review the rationale and neurobiological characteristics that may help to explain why functional neurosurgery has been proposed to control aggressive behavior.

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“…Although there is currently no cure for LP, it does not impact the normal life expectancy of patients. 17 Various treatment modalities have been employed for managing skin lesions, including carbon dioxide lasers, etretinate, acitretin, penicillamine, dimethyl sulfoxide, surgical procedures and dermabrasion. 7 , 18 , 19 Nearly all patients experience laryngeal involvement, and tracheotomy should be considered in cases where severe airway problems are present.…”

Section: Discussionmentioning

confidence: 99%