The EDRN knowledge environment: an open source, scalable informatics platform for biological sciences research

Abstract

We describe here the Early Detection Research Network (EDRN) for Cancer's knowledge environment. It is an open source platform built by NASA's Jet Propulsion Laboratory with contributions from the California Institute of Technology, and Giesel School of Medicine at Dartmouth. It uses tools like Apache OODT, Plone, and Solr, and borrows heavily from JPL's Planetary Data System's ontological infrastructure. It has accumulated data on hundreds of thousands of biospecemens and serves over 1300 registered users across the National Cancer Institute (NCI). The scalable computing infrastructure is built such that we are being able to reach out to other agencies, provide homogeneous access, and provide seamless analytics support and bioinformatics tools through community engagement.

Cancer Biomarkers and Big Data: A Planetary Science Approach

“…The EDRN is a U.S. consortium focusing on the development, discovery, and validation of cancer biomarkers (Srivastava, 2013). Applying data science technologies developed at JPL enabled the development of a novel knowledge system (Figure 1) (Crichton et al, 2010(Crichton et al, , 2017.…”