The EEG in Selected Generalized Seizures

Hrachovy, Richard A.; Frost, James D.

doi:10.1097/01.wnp.0000228496.66246.e0

Cited by 62 publications

(54 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This fi nding may be present in 22.2% to 51.4% of patients 6,19,21 . The myoclonic jerk occurs simultaneously with the Juvenile myoclonic epilepsy Alfradique & Vasconcelos polyspike-and-wave pattern, but the latter continues beyond the termination of the jerk, and may persist for several seconds 24 . There appears to be a correlation between the number of spikes in a given complex and the severity of the associated myoclonic seizure 2 .…”

Section: Electroencephalographymentioning

confidence: 99%

“…The polyspikes are not necessarily followed by slow waves. These bursts may be fragmentary and are usually confi ned to the frontal regions 24 . The typical ictal EEG of a myoclonic seizure displays the pattern of polyspike-and-wave, which consists of a group of 5 to 20 generalized, almost always symmetrical and high frequency (10-16 Hz) spikes, usually followed by slow waves in a frequency of 2,5-5 Hz 2,24,25 .…”

Section: Electroencephalographymentioning

confidence: 99%

“…However, the presence of moderately excessive theta activity and/or alpha rhythm slowness have been described in 28 individuals 7 . Interictal fi ndings include bursts of generalized and irregular spikeand-waves and polyspike-and-waves, in a frequency of 3-5 Hz and frontocentral dominance 24 (Fig 2). The polyspikes are not necessarily followed by slow waves.…”

Section: Electroencephalographymentioning

confidence: 99%

See 2 more Smart Citations

Juvenile myoclonic epilepsy

Alfradique¹,

Vasconcelos

2007

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-Juvenile myoclonus epilepsy (JME) is a common epileptic syndrome, the etiology of which is genetically determined. Its onset occurs from 6 through 22 years of age, and affected patients present with myoclonic jerks, often associated with generalized tonic-clonic seizures -the most common association -and absence seizures. JME is non-progressive, and there are no abnormalities on clinical examination or intellectual deficits. Psychiatric disorders may coexist. Generalized polyspike-and-waves are the most characteristic electroencephalographic pattern. Usual neuroimaging studies show no abnormalities. Atypical presentations should be entertained, as they are likely to induce misdiagnosis. Prevention of precipitating factors and therapy with valproic acid (VPA) are able to control seizures in the great majority of patients. Whenever VPA is judged to be inappropriate, other antiepileptic drugs such as lamotrigine may be considered. Treatment should not be withdrawn, otherwise recurrences are frequent.KEY WORDS: juvenile myoclonic epilepsy, diagnosis, etiology, treatment. Epilepsia mioclônica juvenilRESUMO -A epilepsia mioclônica juvenil é uma síndrome epiléptica comum, cuja etiologia é fundamentada na genética. Inicia-se entre 6 e 22 anos e os indivíduos apresentam mioclonias, que podem ser acompanhadas por crises tônico-clônicas generalizadas -associação mais comum -e crises de ausência. A doença não é progressiva, e não há alterações detectáveis no exame físico ou déficits intelectuais. Distúrbios psiquiátri-cos podem coexistir. Polipontas-ondas lentas generalizadas constituem o padrão eletrencefalográfico ictal típico. Não há anormalidades em exames de imagem convencionais. Apresentações atípicas devem ser consideradas, pois predispõem a erros de diagnóstico. A prevenção de fatores desencadeantes e o uso de áci-do valpróico (VPA) controlam as crises epilépticas na grande maioria dos casos. Quando o VPA é inapropriado, outras drogas como a lamotrigina podem ser utilizadas. O tratamento não deve ser interrompido, visto que as recidivas são freqüentes.

show abstract

Section: Electroencephalographymentioning

confidence: 99%

Section: Electroencephalographymentioning

confidence: 99%

Section: Electroencephalographymentioning

confidence: 99%

See 1 more Smart Citation

Juvenile myoclonic epilepsy

Alfradique¹,

Vasconcelos

2007

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

show abstract

“…There are several seizure types within this class, differing in clinical behavior and in the electroencephalogram (EEG) [10]. One type, the absence seizure (formerly known as petit mal), results in unconsciousness, without convulsions.…”

Section: Epilepsymentioning

confidence: 99%

Coupled Oscillators Model of Hyperexcitable Neuroglial Networks

Farah

Grigorovsky

Bardakjian

2019

Int. J. Neur. Syst.

View full text Add to dashboard Cite

show abstract

“…However, closer inspection of EEG recorded from different subjects (e.g. Hrachovy & Frost 2006) demonstrates a number of different dynamical phenomena, e.g. polyspike and wave discharges and wave-spike discharges, in addition to the classical spike-wave profile (figure 1).…”

Section: Introductionmentioning

confidence: 99%

Onset of polyspike complexes in a mean-field model of human electroencephalography and its application to absence epilepsy

Marten

Rodrigues

Benjamin

et al. 2009

Phil. Trans. R. Soc. A.

121

153

View full text Add to dashboard Cite

In this paper, we introduce a modification of a mean-field model used to describe the brain's electrical activity as recorded via electroencephalography (EEG). The focus of the present study is to understand the mechanisms giving rise to the dynamics observed during absence epilepsy, one of the classical generalized syndromes. A systematic study of the data from a number of different subjects with absence epilepsy demonstrates a wide variety of dynamical phenomena in the recorded EEG. In addition to the classical spike and wave activity, there may be polyspike and wave, wave spike or even no discernible spike-wave onset during seizure events. The model we introduce is able to capture all of these different phenomena and we describe the bifurcations giving rise to these different types of seizure activity. We argue that such a model may provide a useful clinical tool for classifying different subclasses of absence epilepsy.

show abstract

The EEG in Selected Generalized Seizures

Cited by 62 publications

References 41 publications

Juvenile myoclonic epilepsy

Juvenile myoclonic epilepsy

Coupled Oscillators Model of Hyperexcitable Neuroglial Networks

Onset of polyspike complexes in a mean-field model of human electroencephalography and its application to absence epilepsy

Contact Info

Product

Resources

About