The Effect of Bladder Volume on RT Dosimetry during Multiple Sessions of Intracavitary Brachytherapy for Cervical Cancer

Abstract

were 80.8% and 86.8% (P Z 0.188). The DMFS rates were 88.7% and 98.1% (P Z 0.029). The number of cycles of ACT (1 cycle vs. ! 2 cycles) did not affect the prognosis of patients with LACSCC. The tumor marker carbohydrate antigen 125 (CA125) was found to be related with survival time. CA125 > 35 U/mL may be one of the indicators for ACT to improve survival. Conclusion: This study showed that ACT after CCRT is beneficial for DMFS in Chinese patients with LACSCC. In practice, the number of ACT cycles should be carefully considered as appropriate. CA125 may be a relevant factor influencing prognosis, and its value is inversely proportional to survival time. In LACSCC patients with CA125 > 35 U/mL, ACT after CCRT may be more important in improving prognosis compared with CCRT alone.