The Effect of Conduction Exercise and Self‐Acupressure in Treatment of Parkinson’s Disease: A Pilot Study

Yuen, Chun-Sum; Chua, Ka-Kit; Lau, Waihing; Zhuang, Zhiyuen; Chow, Ho-Yan; Li, Min

doi:10.1155/2020/7950131

Cited by 6 publications

(13 citation statements)

References 27 publications

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“…A total of 5 studies did not use massage alone, and 13 studies lacked the outcome measure, UPDRS score. At the end of the selection process, 7 studies met the inclusion criteria ( 16 , 18 , 19 , 21 , 22 , 26 , 27 ) ( Figure 1 ).…”

Section: Resultsmentioning

confidence: 99%

Effectiveness of therapeutic massage for improving motor symptoms in Parkinson's disease: A systematic review and meta-analysis

et al. 2022

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BackgroundParkinson's disease (PD) causes movement disorders [called motor symptoms (MS)], and motor dysfunction poses a great barrier to the quality of life. Although pharmacological therapy like levodopa can relieve the symptoms, it can also cause complications, such as psychosis, nausea, and dyskinesia. A therapy with more minor side effects is needed for PD. Therapeutic massages are the most commonly used forms of complementary and alternative medicine (CAM), but no systematic review and meta-analysis have focused on the efficacy of massage on PD.ObjectiveTo evaluate the quality of evidence and efficacy of therapeutic massage for improving MS in PD.MethodsWe independently searched four electronic databases, including Chinese National Knowledge Infrastructure (CNKI), MEDLINE/PubMed, Embase, and Cochrane Library, for randomized controlled trials (RCTs) about therapeutic massage and other available manual therapies improving MS in PD from January 1, 2012, to December 31, 2021 (recent 10 years). The main outcome measures were total effectiveness and the Unified Parkinson's Disease Rating Scale (UPDRS), including UPDRS total, II, and III. For the statistical analysis, the risk ratio, standard mean difference, and 95% confidence interval (CI) were used to calculate effect sizes between groups. To determine heterogeneity, statistical index I2 was used.ResultsA total of 363 PD participants in seven RCTs and one randomized pilot-control study were included in this meta-analysis. The total effectiveness showed that therapeutic massage was more effective than the intervention of the control group for improving MS [ratio risk (RR): 1.33, 95% CI (1.14–1.55), p = 0.0002]. The UPDRS-III scores showed that massage improves motor function more than the control group [SMD = −0.46, 95% CI (−0.67, −0.24), p < 0.00001]. But we found that massage performed no better than the control group in improving daily life activities [SMD = −0.15, 95% CI (−0.40, 0.10), p = 0.23].ConclusionTherapeutic massage was effective in improving MS in PD. It is suggested to be an appropriate form of CAM in treating PD.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=323182, identifier: CRD42022323182.

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Section: Resultsmentioning

confidence: 99%

Effectiveness of therapeutic massage for improving motor symptoms in Parkinson's disease: A systematic review and meta-analysis

et al. 2022

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“…Table 1 summarizes the detailed information on individual trials. Among them, 19 (28.79%) studies adopted special methods of AT: BVA (Cho et al, 2012 ; Hartmann et al, 2016 ; Cho S. Y. et al, 2018 ), abdominal acupuncture (Wen et al, 2008 ), acupoint injection (Liu et al, 2015 ), self-acupuncture (Yuen et al, 2020 ), catgut embedding (Hu et al, 2014 ; Zhu, 2016 ), moxibustion (Zhang et al, 2005 ; Deng et al, 2014 ; Wu, 2014 ; Shen et al, 2018 , 2019 ), and herbal decoction (Zhang and Jiang, 2010 ; Hu, 2018 ; Xiao and Zhang, 2018 ; Cheng, 2019 ; Huo et al, 2019 ; Zhao, 2019 ).…”

Section: Resultsmentioning

confidence: 99%

“…Yuen et al ( 2020 ) investigated the efficacy of conduction and self-acupressure (CE and SA) for improving PDQ-39 scores in PD patients. They found that CE and SA had the potential to treat non-motor symptoms, but inconclusive effectiveness based on PDQ-39 scores was found between the two groups.…”

Section: Resultsmentioning

confidence: 99%

“…Regarding abdominal acupuncture, due to the painless procedure and effectiveness, it is easy to practice and worthy of clinical promotion (Chen et al, 2007 ). Meanwhile, self-acupressure can be promoted as a home-based therapy and conducive to relieving non-motor symptoms, especially in the gastrointestinal tract (Yuen et al, 2020 ). Moxibustion may be better for non-motor symptoms, especially for PD-related constipation.…”

Section: Discussionmentioning

confidence: 99%

“…Only 13 (19.70%) articles discussed adverse events, two (Cho et al, 2012 ; Xu et al, 2020 ) (3.03%) of which reported that there were no adverse events, and 12 (Jiang X. M. et al, 2006 ; Yang et al, 2006b ; Chen et al, 2012 ; Cho et al, 2012 ; Hartmann et al, 2016 ; Kluger et al, 2016 ; Zhou et al, 2016 ; Kong et al, 2017 ; Cho S. Y. et al, 2018 ; Lin Z. C. et al, 2018 ; Xiao and Zhang, 2018 ; Yuen et al, 2020 ) (18.18%) publications reported the details of adverse events. The remaining two (Chen et al, 2013 ; Hu et al, 2014 ) (3.03%) studies reported that there was no significant change in biochemical parameters after treatment.…”

Section: Discussionmentioning

confidence: 99%

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Acupuncture-Related Therapies for Parkinson's Disease: A Meta-Analysis and Qualitative Review

Wen

et al. 2021

Front. Aging Neurosci.

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Objective: This systematic review and meta-analysis aimed to assess the effects of the combination of acupuncture-related therapies with conventional medication compared with conventional medication in patients with Parkinson's disease (PD).Methods: A literature search within eight databases [including Medline, Embase, the Cochrane Library, PubMed, China National Knowledge Infrastructure (CNKI), China Biology Medicine (CBM), VIP, and Wanfang Database] was performed covering a time frame from their inception to August 2020. Randomized controlled trials (RCTs) comparing acupuncture-related therapies combined with conventional medication vs. conventional medication in patients with PD were eligible. Two authors independently assessed the risk of bias. Assessments were performed with the total and subscales scores of the Unified Parkinson's Disease Rating Scale (UPDRS), 39-item Parkinson's Disease Questionnaire (PDQ-39), the dosage of Madopar, Mini-Mental State Examination (MMSE), and 17-item Hamilton Depression Scale (HAMD). Data were analyzed by adopting the Cochrane Collaboration's RevMan 5.4 (Review Man, Copenhagen, Denmark); and mean effect sizes and 95% confidence intervals were estimated. Tests for heterogeneity were used to assess differences in treatment effects across different types of acupuncture used.Results: Sixty-six trials met the inclusion criteria, of which 61 trials provided data for the meta-analysis. We defined high-quality articles as those with a low risk of bias in four or more domains; and only 10 (15.15%) articles were of high quality. Compared with the controls, acupuncture-related therapies with conventional medication achieved a benefit in the primary outcomes of UPDRS (motor subscore: −3.90, −4.33 to −3.49, P < 0.01; total score: −7.37 points, −8.91 to −5.82, P < 0.001; activities of daily living subscore: −3.96, −4.96 to −2.95, P < 0.01). For the subgroup difference test among the effects of different acupuncture methods, significant differences existed in outcomes with the UPDRS-III, UPDRS-I, UPDRS-IV, and PDQ-39 scores and Madopar dosage, while non-significant differences existed with the UPDRS-total, UPDRS-II, HAMD, and MMSE scores.Conclusions: Acupuncture-related therapies combined with conventional medication may benefit individuals with PD. Our review findings should be considered with caution because of the methodological weaknesses in the included trials. Future, large randomized trials of acupuncture-related therapies for PD with high methodological quality are warranted.Systematic Review Registration: Identifier CRD42021228110.

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Feasibility of self-administered acupressure for allergic rhinitis: a pilot randomized controlled trial and lessons learnt for future studies

Liang

Lenon

et al. 2021

Acupunct Med

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Objectives: Allergic rhinitis (AR) is an immunoglobulin (Ig)E-mediated inflammatory condition that is highly prevalent worldwide. The aim of this pilot trial was to evaluate the feasibility and safety of self-administered acupressure for AR. Methods: A randomized, single-blind, non-specific controlled clinical trial was conducted at Royal Melbourne Institute of Technology (RMIT) University, Melbourne, Australia. Fifteen AR patients were randomized into two groups: self-administered acupressure at five specific acupressure (SA) points or five non-specific acupressure (NSA) points (1 min/point, twice a day), and treated for 4 weeks with an 8-week follow-up period. The primary outcome was the change in 7-point scale symptom severity. Secondary outcomes included the rhinoconjunctivitis quality of life questionnaire and standardized activities (RQLQs), medication usage, adverse events and participants’ opinions of the blinding method. The Statistical Package for the Social Science (SPSS) version 26 was used for data analyses. Results: Fourteen participants completed the study and no major adverse events were reported. No statistically significant differences between SA and NSA groups were identified in 7-point scale symptom severity scores, RQLQs or medication usage. However, participants in the SA group believed that SA was useful for AR and recommended it for self-care. The credibility of the blinding method was successful. No adverse effects were considered to be related to the intervention. Conclusion: Acupressure is feasible and appears to be safe for self-administration by AR sufferers. Experience from this pilot study has guided minor amendments to the protocol. A large-scale randomized controlled trial is warranted to further investigate the efficacy and safety of self-administered acupressure for the management of AR.

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The Effect of Conduction Exercise and Self‐Acupressure in Treatment of Parkinson’s Disease: A Pilot Study

Cited by 6 publications

References 27 publications

Effectiveness of therapeutic massage for improving motor symptoms in Parkinson's disease: A systematic review and meta-analysis

Effectiveness of therapeutic massage for improving motor symptoms in Parkinson's disease: A systematic review and meta-analysis

Acupuncture-Related Therapies for Parkinson's Disease: A Meta-Analysis and Qualitative Review

Feasibility of self-administered acupressure for allergic rhinitis: a pilot randomized controlled trial and lessons learnt for future studies

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