The Effect of Ginger Herbal Drink on Hyperemesis Gravidarum in the First Trimester Pregnant Women

Abstract

BACKGROUND: Hyperemesis gravidarum during pregnancy affects almost all pregnant women and has a significant effect on quality of life, causing discomfort and interfering with daily activities, especially during the first trimester of pregnancy. Pharmacological action to reduce hyperemesis is ginger. Ginger can work by blocking receptors serotonin and causing an antiemetic effect on the gastrointestinal system, thereby reducing nausea and vomiting. AIM: The purpose of this study was to analyze the effect of ginger herbal drink in reducing the level of hyperemesis gravidarum in first trimester pregnant women. METHODS: Design This study used a Quasy Experimental with control group with a pre- and post-test approach. Samples were taken with the Consecutive sampling technique. The sample in this study was 96 respondents who were divided into two groups, namely 48 experimental groups and 48 control groups. Measurements used a pregnancy unique quantification of emesis and nausea questionnaire to measure the severity of nausea and vomiting in 24 h. Measurement of hyperemesis level was measured every day for 7 days of the experiment. Data analysis used Wilcoxon rank test and Mann Whitney. RESULTS: The average level of hyperemesis gravidarum before the intervention of ginger herbal drink in the intervention group was 2.2083 and 2.2292 in the control group with p value = 0.806 which means there was no difference in the average frequency of hyperemesis gravidarum while after being given the intervention, the average level of hyperemesis gravidarum in the intervention group was 3.4375 and 2.2917 in the control group with p value = 0.000, which means that there is a difference in the average frequency level of hyperemesis gravidarum in the intervention group and the control group after being given the intervention. CONCLUSION: Ginger drink given to pregnant women in the first trimester can reduce the level of hyperemesis so that pregnant women do not experience excessive nausea and vomiting. Ginger drinks can be recommended as an herbal treatment that can be consumed by pregnant women with hyperemesis gravidarum.

Potential Protective Effect of Zingiber officinale in Comparison to Rosuvastatin on High-fat diet-induced Non-alcoholic Fatty Liver Disease in Rats

“…This agrees with the previous findings [34], [35] which recorded that ginger decreased the concentration of MDA in rats and so decreased the lipid peroxidation. Ginger also given to pregnant women in the first trimester safely [36]. In contrast to our results, Abd-Allah et al [37] observed that using of ginger solution for 6 days in 40 rats showed no effect on MDA level of normal rats.…”

Complementary Therapies in Reducing of Emesis Gravidarum

“…The results of this study are in line with research conducted by Adibah (2022) on The Effect of Ginger Herbal Drink on Hyperemesis Gravidarum in the First Trimester Pregnant Women. The average level of emesis gravidarum before the intervention of ginger herbal drink in the intervention group was 2.2083 and 2.2292 in the control group with p value = 0.806 which means there was no difference in the average frequency of emesis gravidarum while after being given the intervention, the average level of emesis gravidarum in the intervention group was 3.4375 and 2.2917 in the control group with p value = 0.000, which means that there is a difference in the average frequency level of emesis gravidarum in the intervention group and the control group after being given the intervention (Abidah et al, 2022).…”

“…The chemical constituents of ginger are shogaols, gingerols, bisapolene, zingiberene, zingiberol, Abidah et al The Effect of Ginger Herbal Drink on Hyperemesis Gravidarum in the First Trimester Pregnant Women, sesquiphellandrene, essential oils, and resins. Ginger contains flying oil (essential oil) which is refreshing and blocks the gag reflex, while gingerols and shogaols can improve blood circulation and nerves work well and have anti-nausea, anti-vomiting, analgesic, sedative, antipyretic, and anti-bacterial effects (Abidah et al, 2022).…”

The efficacy and safety of complementary and alternative medicine in the treatment of nausea and vomiting during pregnancy: A systematic review and meta-analysis

“…A total of 33 articles ( 24 – 56 ) were included in this paper, of which 24 RCTs ( 24 , 26 – 30 , 33 , 35 , 37 – 44 , 46 , 49 – 53 , 55 , 56 ) were analyzed for quantitative analysis due to sufficient sample size data. The remaining 9 articles ( 25 , 31 , 32 , 34 , 36 , 45 , 47 , 48 , 54 ) were about side effects, for which there were only descriptive discussions provided due to the small sample size data. Three articles ( 24 , 35 , 37 ) only offered the median and interquartile range, which we algorithmically converted to the mean and standard deviation ( 23 ).…”

“…The included RCTs were published from 2002 to 2022. Eleven ( 24 , 27 – 29 , 31 , 33 , 35 , 36 , 38 , 39 , 45 ) were conducted in Iran, five ( 25 , 30 , 37 , 40 , 41 ) in Thailand, five ( 26 , 32 , 47 , 49 , 55 ) in Australia, four ( 43 , 51 – 53 ) in China, two ( 42 , 44 ) in Malaysia, two ( 46 , 54 ) in the UK, one ( 50 ) in Sweden, one ( 34 ) in Indonesia, one ( 48 ) in the USA, and one ( 56 ) in Croatia. The sample sizes of the included RCTs ranged from 18 to 340.…”