The Effect of Prolonged Thyroxine Treatment on the Ageing Male Rat

Everitt, Arthur V.

doi:10.1159/000210829

Search citation statements

Order By: Relevance

Paper Sections

Select...

Therapeutic Applications1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1962

1986

Publication Types

Select...

Article6

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 6 publications

(1 citation statement)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The concept of “euthyroid hypometabolism,” based on the notion that triiodothyronine is “the peripherally active form of thyroxine,” has yet to be established (60, 61), although it is interesting to speculate about in connection with the reported decrease in the rate of disappearance of radiothyroxine in senescence. A study in rats showed no prolongation of life when thyroxine was administered and a slight increase in mortality during the actual period of administration (62). In another study thyroid was administered to old rats for ten months, after which they were studied at autopsy (63, 64).…”

Section: Therapeutic Applicationsmentioning

confidence: 99%