The effect of surgery for endometrioma on ovarian reserve evaluated by antral follicle count: a systematic review and meta-analysis

Muzii, Ludovico; Tucci, Chiara Di; Feliciantonio, Mara Di; Marchetti, Cláudia; Perniola, Giorgia; Panici, Pierluigi Benedetti

doi:10.1093/humrep/deu199

Cited by 170 publications

(130 citation statements)

References 52 publications

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“…The causes may be genetic (107), environmental, infective (subsequent to mumps infection), associated with autoimmune conditions, metabolic [due to biochemical damage in the presence of galactossaemia (174)], and subsequent to cancer therapy (138) or surgery (230); however, in the majority of cases no cause is determined (128). A positive family history exists in 10 -15% of cases with the suggestion that inheritance is autosomal dominant sex-linked or X-linked with incomplete penetrance (357).…”

Section: Geneticmentioning

confidence: 99%

Physiological Aspects of Female Fertility: Role of the Environment, Modern Lifestyle, and Genetics

Hart

2016

Physiological Reviews

174

119

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Across the Western World there is an increasing trend to postpone childbearing. Consequently, the negative influence of age on oocyte quality may lead to a difficulty in conceiving for many couples. Furthermore, lifestyle factors may exacerbate a couple's difficulty in conceiving due mainly to the metabolic influence of obesity; however, the negative impacts of low peripheral body fat, excessive exercise, the increasing prevalence of sexually transmitted diseases, and smoking all have significant negative effects on fertility. Other factors that impede conception are the perceived increasing prevalence of the polycystic ovary syndrome, which is further exacerbated by obesity, and the presence of uterine fibroids and endometriosis (a progressive pelvic inflammatory disorder) which are more prevalent in older women. A tendency for an earlier sexual debut and to have more sexual partners has led to an increase in sexually transmitted diseases. In addition, there are several genetic influences that may limit the number of oocytes within the ovary; consequently, by postponing attempts at childbearing, a limitation of oocyte number may become evident, whereas in previous generations with earlier conception this potentially reduced reproductive life span did not manifest in infertility. Environmental influences on reproduction are under increasing scrutiny. Although firm evidence is lacking however, dioxin exposure may be linked to endometriosis, phthalate exposure may influence ovarian reserve, and bisphenol A may interfere with oocyte development and maturation. However, chemotherapy or radiotherapy is recognized to lead to ovarian damage and predispose the woman to ovarian failure.

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Section: Geneticmentioning

confidence: 99%

Physiological Aspects of Female Fertility: Role of the Environment, Modern Lifestyle, and Genetics

Hart

2016

Physiological Reviews

174

119

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“…After surgery, AFC of the operated ovary did not change essentially if compared to the preoperative qualities for a similar ovary. Additionally, non-excisional methods showed up not to influence AFC values after surgery (28).…”

Section: Histopathological Evaluationmentioning

confidence: 91%

Impact of Laparoscopic Ovarian Cystectomy Versus Laparoscopic Coagulation on Ovarian Reserve in Cases of Ovarian Endometrioma

Shalal

El-Sayed

Mahdy

et al. 2017

Zagazig University Medical Journal

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“…Ön çalışmalar her iki olasılığın da katkıda bulunduğunu düşündürmektedir çünkü antral folikül sayısı endometriomalı overlerde, kist olmayan karşı taraf overe göre hem ameliyat öncesinde hem de ameliyat sonrasında daha düşük bulunmaktadır. 11 Cerrahinin over rezervi üzerine olumsuz etkisi nedeniyle; daha önce ameliyat olmuş kadınlarda, over rezervi zaten düşük olanlarda ve bilateral endometrioma olgularında cerrahi kararı verirken iyi düşünmek gerekmektedir.…”

Section: Cerrahi̇ Tedavi̇unclassified

Management of Infertility in Women with Endometriosis

Sarıdoğan¹,

Saridogan²

2017

TJRMS

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ndometriozis, infertil kadınlarda sıklıkla karşılaştığımız bir durumdur ancak endometriozisle infertilite arasındaki bağlantı hala tartışmalıdır. Laparoskopi, yüksek rezolüsyonlu ultrasonografi ve manyetik rezonans görüntüleme gibi kullanılan tanısal yöntemlerin zaman içinde gelişimi, tetkik edilen endometriozis tipini giderek değiştirmiştir. Bunun yanında, laparoskopik cerrahi ve yardımcı üreme tekniklerindeki gelişmeler de kullanılan tedavi yaklaşımlarını giderek değiştirmekte, bazen bu değişimin hızı Endometriozisin gelecekte infertilite riskini artırdığına dair ikna edici birçok kanıt vardır. Erken evre endometrioziste azalmış fertilitenin patogenezi tam olarak bilinmemekle birlikte evre III ve IV endometriozisteki pelvik anatomi distorsiyonunun infertiliteden sorumlu olduğu düşünülmektedir. Hem erken ve hem de ileri evre endometriozis için yapılan laparoskopik cerrahi spontan gebelik oranlarını iyileştirmekte yararlıdır. Açıklanamayan infertilitesi olanlar dışındaki iyi over rezervli genç kadınlarda cerrahi ilk seçenek olabilir. Erkek faktör infertilitesi veya tubal hasar birlikteliği ya da diğer yaklaşımların başarısızlığı söz konusu olduğunda endometriozis ilişkili subfertilitede yardımcı üreme teknikleri tercih edilecek tedavidir. Diğer tanısal kategorilere kıyasla endometriozisli kadınlarda yardımcı üreme tekniklerinin klinik gebelik oranları daha düşük görünse de, geniş ulusal veritabanlarından alınan verilerin sonuçları bunun aksini göstermektedir.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Endometriozis; infertilite; yönetim A AB BS S T TR RA AC CT TThere is convincing evidence that endometriosis increases future risk of infertility. The pathogenesis of reduced fertility in early endometriosis is not clearly known but distortion to pelvic anatomy in stage III and IV endometriosis is likely to be responsible for infertility. Laparoscopic surgery for both early and advanced endometriosis is beneficial in improving spontaneous conception rates. Surgery may be the first choice in young women with good ovarian reserve and otherwise unexplained infertility. However, assisted reproductive technology (ART) is the preferred treatment in endometriosis associated subfertility when there is concomitant male factor infertility or tubal damage or when other approaches have failed. Clinical pregnancy rates of ART may be lower in women with endometriosis compared to other diagnostic categories, however this is disputed on the basis of data from large national databases. ART does not appear to increase the risk of recurrent endometriosis. Ya zış ma Ad re si/Cor res pon den ce:

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The effect of surgery for endometrioma on ovarian reserve evaluated by antral follicle count: a systematic review and meta-analysis

Abstract: No external funding was sought or obtained for this study. No conflicts of interest are declared.

Cited by 170 publications

References 52 publications

Physiological Aspects of Female Fertility: Role of the Environment, Modern Lifestyle, and Genetics

Physiological Aspects of Female Fertility: Role of the Environment, Modern Lifestyle, and Genetics

Impact of Laparoscopic Ovarian Cystectomy Versus Laparoscopic Coagulation on Ovarian Reserve in Cases of Ovarian Endometrioma

Management of Infertility in Women with Endometriosis

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