“…This phenomenon of pupal attachment holds great significance for insect survival, serving several essential purposes such as preventing displacement by predators, enhancing resilience against environmental factors like wind or rain, and facilitating the emergence of adults from pupae during metamorphosis [ 15 , 16 , 62 ]. Additionally, the knockdown of MsCarE14, MsCarE28, and MsCCE001h in Mythimna separata (Lepidoptera, Noctuidae) resulted in reduced susceptibility to CGA (Chlorogenic acid), a potential botanical insecticide metabolite naturally occurring in various plants, underscoring the crucial roles of these three CarEs in CGA detoxification [ 63 ].…”