Vinasse-molasses, the residue of condensed molasses is a co-product of sugar production. It is not reused in manufacturing process and become polluted. However, Its contents of 48-60% of sugar and high in potassium and sulphates. This study was to evaluate Vinasse-molasses utilization as a replacer of molasses in finishing ration on the growth performance of Peranakan Ongole Cattle. A total of 10 Peranakan Ongole cattle (initial body weight of 209 ± 21 kg) were assigned to molasses group or Vinasse-molasses group. The experiment period was lasted 68 days, preceded by 14 days adaptation period. The experimental diet was composed of 20% forage and 80% concentrate containing 15% molasses or Vinasse-molasses. Parameters observed including final body weight (FBW), average daily gain (ADG), total dry matter intake (DMI), forage intake, concentrate intake, feed efficiency (FE), and income over feed cost (IOFC). The Vinasse-molasses reduced (P<0.05) DMI and concentrate intake followed by IOFC increased (P<0.01) of cattle. However, Vinasse-molasses did not affect (P>0.05) FBW, ADG, forage intake, and FE. It can be concluded that Vinasse-molasses can be utilize as feed ingredient to replace molasses in finishing ration to support the sustainability of beef production.