The Effectiveness Analysis of Selected Radiosurgery Devices on Treatment of Cancer Tumors and Arteriovenous Malformations: A Systematic Review

Abstract

A885to be significantly higher in TKIs group compared with chemotherapy group. The most common reported adverse events with TKIs were rash, diarrhoea, acne, dry skin and pruritis. Liver enzyme elevations and interstitial lung disease has also been seen in TKIs patients. In view of economic analysis, inclusion of Gefitinib as first line was found to be a dominant strategy based on three landmark studies. In contrast, Erlotinib was reported to yield both lower cost and quality adjusted life years (QALY). ConClusions: Moderate to high level of evidence showed that TKIs significantly prolonged the progression free survival of NSCLC patient but not overall survival and increase the overall response rates in chemo-naive patient with positive EGFR gene mutation.