The Effectiveness of Mugwort Leaf Extract and Gotu Kola Leaf Extract against Acne Bacterial Activity

Sari, Diah Puspita; Yuniar, Shintya; Fadillah, Siti Awalia Nur; Mutiarani, Afifi; Kusumawaty, Diah

doi:10.17509/ajse.v2i3.39634

Cited by 3 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In several studies, Flavonoids found in Gotu kola leaves have been shown in multiple trials to reduce acnecausing bacteria (Sari et al, 2022). As a natural disinfectant, a mixture of 1:1 Gotu Kola extract and Aloe Vera can be effective (Mayefis et al, 2023a).…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activity Test of Gotu Kola Leaf Extract (Centella asiatica) Against Staphylococcus aureus Bacteria Isolated from Wounds of Diabetes Mellitus Patients

Fioni,

Heldayani,

Lister

et al. 2023

jppipa, pendidikan ipa, fisika, biologi, kimia

View full text Add to dashboard Cite

Staphylococcus aureus, a gram-positive bacterium, is the causative agent of diabetic foot. Traditional medicine using plants needs much further research, especially for wound healing in diabetes mellitus patients. This study is an experimental laboratory investigation on the efficacy of Gotu kola (Centella asiatica) leaf extract against wound-isolated Staphylococcus aureus. Gotu kola leaf extract (12.5%, 25%, 50%, 75%, and 100%), cefixime suspension (positive control), and sterile distilled water were tested. The results of the research showed the formation of an inhibitory zone from testing Gotu kola leaf extract against Staphylococcus aureus bacteria, where the average inhibitory zone was at concentrations of 12.5% (7.2 mm), 25% (11 mm), 50% (13.7 mm), 75% (14 .3 mm), and 100% (19.5 mm). The higher the concentration used, the larger the inhibition zone formed. Research shows that Gotu kola leaves' active substances inhibit energy formation, nucleic acid formation, cell membrane permeability, structure and function, and membrane protein lysis and damage.

show abstract

Section: Introductionmentioning

confidence: 99%

Antibacterial Activity Test of Gotu Kola Leaf Extract (Centella asiatica) Against Staphylococcus aureus Bacteria Isolated from Wounds of Diabetes Mellitus Patients

Fioni,

Heldayani,

Lister

et al. 2023

jppipa, pendidikan ipa, fisika, biologi, kimia

View full text Add to dashboard Cite

show abstract

Formulation, physical characterization, and antibacterial activity of modifications of Bawang Dayak Eleutherine bulbosa (Mill.) Urb. anti-acne cream

Novaryatiin,

Nuramanah,

Isnawati

et al. 2024

Journal of Herbal Medicine

View full text Add to dashboard Cite

The Effect of a Combination of Black Tea With Pegagan Leaf Tea (Centella Asiatica) on Ph, Total Acid, and Flavonoids

PURWANI,

PUTRI,

SOFYAN

2024

Int J App Pharm

View full text Add to dashboard Cite

Objective: There is no further research related to the development of Pegagan leaves; this innovation is expected to be able to process a product that is useful for health, one of which can be used as a functional drink. Therefore from that, he purpose is to research the effects of the combination of black tea with Pegagan leaves (Centella asiatica) on pH, total acids, and flavonoids. Methods: The type of this study was experimental. This study was conducted by combining black tea with different Pegagan leaves. The research design used a Completely Randomized Design with 3 combinations of Pegagan leaves in black tea, which were P1 (0%:100, P2(25%:75), and P3(50%:50). Results: The results showed the highest flavonoid levels in the combination of black tea with P3 Pegagan leaf tea (50%:50%) of 0.020%. There was no significant effect on the pH value and total acid content. However, on the flavonoid content, there was a significant effect on the combination of black tea and Pegagan leaf tea. Conclusion: Based on the results of the study, it can be concluded that the combination of black tea and Pegagan leaf tea had no effect on pH value (p=0.911) and total acids (p=0.749). In the flavonoid level, the results of the study showed that there was an effect on the combination of black tea and Pegagan leaf tea (p=0.007).

show abstract

The Effectiveness of Mugwort Leaf Extract and Gotu Kola Leaf Extract against Acne Bacterial Activity

Cited by 3 publications

References 8 publications

Antibacterial Activity Test of Gotu Kola Leaf Extract (Centella asiatica) Against Staphylococcus aureus Bacteria Isolated from Wounds of Diabetes Mellitus Patients

Antibacterial Activity Test of Gotu Kola Leaf Extract (Centella asiatica) Against Staphylococcus aureus Bacteria Isolated from Wounds of Diabetes Mellitus Patients

Formulation, physical characterization, and antibacterial activity of modifications of Bawang Dayak Eleutherine bulbosa (Mill.) Urb. anti-acne cream

The Effect of a Combination of Black Tea With Pegagan Leaf Tea (Centella Asiatica) on Ph, Total Acid, and Flavonoids

Contact Info

Product

Resources

About