The effectiveness of the use of biotinylated derivative of oxidized dextran in the prevention of subclinical mastitis of cows

Abstract

Prevention of cow mastitis remains an urgent problem in veterinary medicine. The majority of subclinical mastitis resulting from a violation of the milking regime, in the absence of adequate therapy, turn into a clinical form, complicated by the involvement of representatives of conditionally pathogenic microflora in the process. To prevent the development of such complications, agents that activate the cellular and humoral immunity system are used.The article presents the results of a study of the use of biotinylated derivative of oxidized dextran (DOD) in the prevention of subclinical mastitis of cows.The data obtained in the course of the work showed a high preventive effectiveness of DOD. In the experimental group, a dynamic decrease of somatic cells by 16.85% relative to the control was observed on day 4-5. Starting from the second administration of the drug, stable low values of somatic cells were observed in the experimental group, whereas in the control group animals were identified that respond positively to Kenotest, which together with an increase in somatic cells indicates the development of latent (subclinical) mastitis.