The effectiveness of three mobile-based psychological interventions in reducing psychological distress and preventing stress-related changes in the psycho-neuro-endocrine-immune network in breast cancer survivors: Study protocol for a randomised controlled trial

Světlák, Miroslav; Malatincová, Tatiana; Halámková, Jana; Barešová, Zdeňka; Lekárová, Monika; Vigašová, Dana; Slezáčková, Alena; Šumec, Rastislav; Humpolíček, Pavel; Šedo, Jiří; Chládek, Jan; Román, Róbert; Gottwaldová, Jana; Gescheidtová, Lenka; Čermáková, Zdeňka; Thon, Vojtěch; Hrnčiříková, Iva; Kazda, Tomáš; Svoboda, Marek

doi:10.1016/j.invent.2023.100628

Cited by 3 publications

(3 citation statements)

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“…Changes in hormone levels in the endocrine system can also affect the levels of immune cells and inflammatory cytokines, resulting in changes in the immunological microenvironmental homeostasis ( 48 , 49 ). Additionally, MI can activate central and peripheral immune cells, leading to the release of proinflammatory cytokines, proinflammatory cytokines pass through the blood–brain barrier to reach the brain, creating a vicious cycle, that is consistent with the vicious cycle caused by MI and LBP ( 50 , 51 ).…”

Section: Discussionmentioning

confidence: 63%

Mood instability and low back pain: a mendelian randomization study

Liu,

et al. 2023

Front. Neurol.

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ObjectiveLow back pain is a prevalent and debilitating condition worldwide, with significant implications for individuals’ quality of life and productivity. The aim of this study was to assess the relationship between mood instability and the risk of developing chronic low back pain, using a rigorously designed mendelian randomization methodology.MethodThe study incorporated both univariate and multivariate mendelian randomization to analysis the causal relationship between mood instability and the risk of developing chronic low back pain. The data on mood instability from the Integrative Epidemiology Unit (IEU) opened Genome-Wide Association Studies (GWAS) project (IEU-opened GWAS project). Data on low back pain were collected from two sources: One source is the IEU open GWAS project (discovery data). Another source is a GWAS meta-analysis (replication data). Inverse variance weighted method, weighted median method, MR-Egger regression, and mendelian randomization pleiotropy residual sum and outlier method were used for mendelian randomization analysis.ResultThe univariable mendelian randomization analysis shows a statistically significant correlation between mood instability and the risk of low back pain. Several methods were performed, including inverse variance weighting (discovery data: odds ratio = 3.544, 95% confidence interval = 1.785–7.039, p = 0.000; replication data: odds ratio = 3.167, 95% confidence interval = 2.476–4.052, p = 0.000), MR-Egger (discovery data: odds ratio = 7.178, 95% confidence interval = 0.057–909.525, p = 0.429; replication data: odds ratio = 2.262, 95% confidence interval = 0.580–8.825, p = 0.246), weighted median (discovery data: odds ratio = 2.730, 95% confidence interval = 1.112–6.702, p = 0.028; replication data: odds ratio = 3.243, 95% confidence interval = 2.378–4.422, p = 0.000), MR-PRESSO (discovery data: odds ratio = 3.544, 95% confidence interval = 1.785–7.039, p = 0.001; replication data: odds ratio = 3.167, 95% confidence interval = 2.476–4.052, p = 0.000) methods. The results were consistent across these methods. The results obtained from discovery data are consistent with those obtained from discovery data. In the multivariable mendelian randomization, after adjusting for various covariates such as body mass index, current tobacco smoking, alcohol intake frequency, Total body bone mineral density, and vigorous physical activity, there is a consistent correlation between mood instability and chronic low back pain.ConclusionThis study provides robust evidence supporting a causal relationship between mood instability and the development of low back pain. Our findings suggest that addressing mood instability may play a crucial role in prevention and management strategies for individuals experiencing low back pain.

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Section: Discussionmentioning

confidence: 63%

Mood instability and low back pain: a mendelian randomization study

Liu,

et al. 2023

Front. Neurol.

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“…The keyword burst (Figure 7) changed to "meta-analysis", "older adult", "strategy", "psychological distress", "technology", "prostate cancer" and "mobile application". The research hotspots are based on the use of modern technology such as mobile devices for psychological interventions for breast cancer patients (30), pain interventions (31)and other measures to promote self-management, and it is expected that the literature in this area of research is likely to continue to grow and the research will become more in-depth. (35), and that quality of life scores may be a marker of patients' behavioural and perceptual societies.…”

Section: Keyword Co-occurrence Analysismentioning

confidence: 99%

“…There are related studies on the importance of access to lymphoedema treatment and related resources through timely and continuous self-management education for breast cancer survivors to prevent and manage lymphoedema. effective in self-management behaviours (41,42), self-management skills (43)(44)(45), and the management of adverse effects (46), complication management (47,48), medication management(49), dietary management(50), exercise management(51), emotional management (30,52), among others.…”

Section: Keyword Co-occurrence Analysismentioning

confidence: 99%

Current status and hotspots in breast cancer patient self-management research: a bibliometric and visual analysis via CiteSpace (Preprint)

Chen,

Huang,

Chen

et al. 2023

Preprint

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BACKGROUND Breast cancer is the most common cancer in women and the leading cause of cancer-related deaths among women worldwide.With significant improvements in breast cancer screening, diagnosis and treatment, the number of breast cancer survivors has significantly increased.Individuals with chronic illnesses often develop self-management skills as they cope with their condition, and these include: management of disease symptoms, detection of physiological and psychosocial changes, and lifestyle changes.Fewer studies have systematically summarised the hotspots, pathways and trends in self-care of breast cancer patients, and information on the history, current status and future trends of studies related to self-management of breast cancer patients is incomplete. OBJECTIVE Purpose: To analyze the current status, hotspots, and research trends related to self-management in breast cancer patients from 2005 to 2023 using Citespace on the Web of Science core database. METHODS Method: A search was conducted in the WoSCC from January 1, 2005, to August 31, 2023. The literature was visualised and analysed by CiteSpace 6.1.R6 for publication time, number of articles, country distribution, institutional distribution, reference co-citation, and keywords. RESULTS Results: A total of 1,413 English-language documents were included in the research on self-management of breast cancer patients from 2005 to 2023. The USA had the highest amount of issuance, while the University of Toronto had the most among institutions. The reference with the highest number of co-citations was "Self-Management: Enabling and empowering patients living with cancer as a chronic illness. "High-frequency keywords are quality of life, chronic disease, self-management, patient education, randomised controlled trials, education, intervention. These keywords formed 11 clusters related to the content of the intervention, the way of the intervention, outcome indicators, keyword burst analysis predicted that future research hotspots would focus on patient needs, psychological distress, internet technology, and mobile apps. CONCLUSIONS Conclusions: The research on breast cancer self-management is expanding rapidly. To further promote the development in this field, it’s crucial to strengthen cooperation and communication between different countries/regions and institutions. The findings suggest that there’s a need for more research in this field, particularly in areas such as patient needs and the use of technology to improve breast cancer patient self-management. Additionally, our findings offer suggestions for future research.

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Current status and hotspots in breast cancer patient self-management research: A bibliometric and visual analysis via CiteSpace

Chen,

Cao,

Huang

et al. 2024

Medicine

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Background: Breast cancer remains a leading cause of cancer-related mortality worldwide. Patient self-management plays a pivotal role in enhancing outcomes and quality of life for individuals affected by this disease. This study employed bibliometric and visual analysis techniques utilizing CiteSpace to elucidate the current status and research hotspots in breast cancer patient self-management from January 1, 2005, to August 31, 2023. Methods: A comprehensive search was conducted in the Web of Science Core Collection (WoSCC). The retrieved literature was subjected to visualization and analysis using CiteSpace, focusing on publication timeline, article count, geographical distribution, institutional affiliations, journal sources, reference co-citation networks, and keyword analysis. Results: The analysis encompassed 1413 English-language documents. The United States emerged as the most prolific contributor, while the University of Toronto demonstrated the highest institutional output. The two-map overlay revealed prominent citation paths, indicating strong interconnections between publications in “Medicine, Medicine, Clinical” and “Health, Nursing, Medicine,” as well as “Psychology, Education, Health” and “Health, Nursing, Medicine.” The most frequently co-cited reference was “Self-Management: Enabling and Empowering Patients Living with Cancer as a Chronic Illness.” High-frequency keywords identified included quality of life, chronic disease, self-management, patient education, randomized controlled trials, education, and intervention. These keywords formed 11 distinct clusters related to intervention content, methodologies, outcome indicators, and emerging research trends. Keyword burst analysis predicted future research hotspots focusing on patient needs, psychological distress, Internet technology, and mobile applications. Conclusions: Research in breast cancer self-management is experiencing significant growth. Enhanced collaboration between countries, regions, and institutions is imperative. Further investigation is warranted, particularly in the domains of “quality of life,” “patient education,” and “mobile health.” These findings provide valuable insights to guide future research directions in this critical field.

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The effectiveness of three mobile-based psychological interventions in reducing psychological distress and preventing stress-related changes in the psycho-neuro-endocrine-immune network in breast cancer survivors: Study protocol for a randomised controlled trial

Cited by 3 publications

References 40 publications

Mood instability and low back pain: a mendelian randomization study

Mood instability and low back pain: a mendelian randomization study

Current status and hotspots in breast cancer patient self-management research: a bibliometric and visual analysis via CiteSpace (Preprint)

Current status and hotspots in breast cancer patient self-management research: A bibliometric and visual analysis via CiteSpace

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