The Effectiveness of Vitamin E Soft Capsules as an Antioxidant

Abstract

Antioxidants inhibit the oxidation of other molecules and play an important role in maintaining a healthy body. Antioxidants are found in fruits, vegetables, all parts of plants, and are present in the body as enzymes or products of metabolism. Vitamin E refers to a large number of natural or synthetic compounds, with alpha-tocopherol being the most active and widely distributed form in nature. Alpha-tocopherol is the most active antioxidant form of vitamin E and serves as the primary lipophilic antioxidant in plasma, membranes, and tissues. The most important function of vitamin E is its antioxidant capability, counteracting free radical attacks that can damage cells and cause various degenerative diseases. Additionally, antioxidants help reduce the effects of photoaging on the skin, potentiate anti-aging and anti-inflammatory activity, increase the rate of wound healing, and help maintain healthy eyes and the immune system. One form of vitamin E dosage form is a soft capsule which has several advantages, including the ease of filling the Active Pharmaceutical Ingredient (API) in liquid form, higher production capacity and formulation uniformity compared to gelatin tablets or hard capsules. Soft capsule preparations also have rapid API release, which can result in achieving therapeutic blood levels more quickly and achieving greater bioavailability. This study aims to evaluate soft capsule dosage forms in enhancing the effectiveness of vitamin E as an antioxidant. The research utilizes review articles sourced from national and international journals, as well as scientific journals. The results show that vitamin E supplementation in soft capsules can increase its effectiveness as an antioxidant.