“…Studies have been performed to evaluate the pharmacokinetics of BZL in healthy subjects [7,[9][10][11][12][13][14], the elderly [15] and patients with hypertension, major proteinuria, or liver cirrhosis [7,16,17]. Sun et al [9] reported that after a single oral administration of 10 mg benazepril hydrochloride tablet to 12 healthy male Caucasians in South Wales, UK, the mean area under the plasma concentration-time curve (AUC 0-4 h ), maximum plasma concentration (C max ) and time to C max (t max ) values for BZL were 140 ng h/mL, 149 ng/mL, and 0.6 h, respectively; while the mean AUC 0-24 h , C max , and t max values for BZT were 1410 ng h/mL, 257 ng/mL, and 1.5 h, respectively.…”