1976
DOI: 10.1016/s0003-0465(16)33766-1
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The Effects of Caffeine

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Cited by 6 publications
(3 citation statements)
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“…2). Caffeine has been suggested to be a hyperglycemic agent (10,34), enhancing hepatic cAMP activity, thus stimulating glycogenolysis (32) and, in turn, insulin secretion (33). This response, however, is unlikely in view of more recent studies on the interrelationships of elevated FFA use and suppressed glucose uptake (27) and lower overall carbohydrate metabolism (12,13,19,20,25,27).…”
Section: Resultsmentioning
confidence: 99%
“…2). Caffeine has been suggested to be a hyperglycemic agent (10,34), enhancing hepatic cAMP activity, thus stimulating glycogenolysis (32) and, in turn, insulin secretion (33). This response, however, is unlikely in view of more recent studies on the interrelationships of elevated FFA use and suppressed glucose uptake (27) and lower overall carbohydrate metabolism (12,13,19,20,25,27).…”
Section: Resultsmentioning
confidence: 99%
“…On each occasion caffeine,‡ 4 mg/kg, was given intravenously during 30 minutes. This dose was designed to achieve a peak plasma caffeine level similar to that produced by the ingestion of two to three cups of brewed coffee 5 …”
Section: Methodsmentioning
confidence: 99%
“…Caffeine elevates respiratory and metabolic rate (Lombardo, 1986), acts as a diuretic on kidneys (Bellet, Roman, DeCastro, Kim & Kershbaum, 1969), reduces liver and mesenteric blood flow (Onrot, Goldberg, Biaggioni, Hollister & Kincaid, 1985;Onrot, Shaheen, Biaggioni, Golbert & Feely, 1986), leads to colon anxiety (Cines & Rozin, 1982), reduces competence of the esophageal sphincter muscle (i.e., heartburn; Bunker & McWilliams, 1979), affects vagal, medullary and vasomotor centers (Syed, 1976). At high concentrations, caffeine collects in muscle tissue (Burg, 1975) and can interfere with neuromuscular transmission (VanHandle, 1983, pg.…”
Section: Effects Of Caffeine Usementioning
confidence: 99%