The effects of three different low-molecular-weight heparins on blood loss after intramedullary nailing of trochanteric fractures

Abstract

Purpose The purpose of this study was to compare the effects of reviparin, dalteparin and enoxaparin on intraoperative blood loss in patients with trochanteric fracture treated with intramedullary nailing. Materials and methods This retrospective multicenter study included 100 patients with trochanteric fracture who were divided into three groups according to the low-molecular-weight heparin administered. In all cases, a short third generation Gamma nail was used for osteosynthesis. Complete blood count and number of red blood cell transfusions (RBC) were evaluated. Results The mean value of postoperative haemoglobin level was lower in the enoxaparin group compared to the reviparin group, with significant difference ( p = 0.001; 95% CI 4.1–18.87). Patients in the dalteparin group received more RBC transfusions compared to the reviparin and enoxaparin group ( p = 0.048). Conclusion The use of enoxaparin and dalteparin in hip fracture patients can result in lower postoperative haemoglobin levels and more RBC transfusions compared to reviparin.