The Endometrial Cups and Allantochorionic Pouches in the Mare With Emphasis on the Source of Equine Gonadotrophin

Clegg, M. T.; Boda, J. M.; Cole, H. H.

doi:10.1210/endo-54-4-448

Cited by 76 publications

(31 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…hormone. These values, like those for blood, are greatly depressed compared with values for mares bred to a stallion (see Cole & Goss, 1943;Clegg et al, 1954). -, mare 860 bred to stallion; ·-·, mare 814 bred to jack; -, mare 860 bred to jack.…”

Section: Resultsmentioning

confidence: 98%

“…Clegg, Boda & Cole (1954) provided evidence that the hormone was secreted by the epithelial cells fining the uterine lumen and the uterine glands in the cup area. They pointed out, furthermore, that the cups were formed in the portion of the endometrium which is apposed to the allantochorion where the blood vessels fan out from the umbilical vessels.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Influence of Foetal Genotype on Equine Gonadotrophin Secretion

Clegg¹,

Cole²,

Howard³

et al. 1962

Journal of Endocrinology

Self Cite

View full text Add to dashboard Cite

The serum concentration of gonadotrophin during several stages of pregnancy was determined in seven mares bred to a stallion and in four mares bred to a jack. To eliminate individual differences, two mares were bred successively to a stallion and to a jack. When the mare is carrying a mule foetus the hormone concentration is approximately one-tenth that associated with a horse foetus. One mare carrying a mule foetus was killed on the 69th day of pregnancy. Though the endometrial cups appeared normal histologically, the endometrial cup secretion was scanty and low in potency.The amount of hormone in the cups themselves was also low.The genotype of the foetus, we conclude, influences the secretory activity of the endometrial cups.

show abstract

Section: Resultsmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

The Influence of Foetal Genotype on Equine Gonadotrophin Secretion

Clegg¹,

Cole²,

Howard³

et al. 1962

Journal of Endocrinology

Self Cite

View full text Add to dashboard Cite

show abstract

“…Here, they suddenly become sessile, enlarge greatly, begin to secrete the unique equine chorionic gonadotrophin (eCG) and become clumped together in the endometrial stroma to form a structure known as an endometrial cup (Schauder 1912, Cole & Goss 1943. Collectively, these endometrial cups comprise a circle of pale, raised endometrial protuberances at the base of the gravid horn which, in time, become ulcer-like in appearance due to overgrowth at the periphery and commencing degeneration in the central region of the structure (Clegg et al 1954, Amoroso 1955. They reach their maximum size and hormone secreting capacity between days 55 and 70 of gestation and thereafter become increasingly pale and degenerate in appearance until they are eventually sloughed off the surface of the endometrium between days 90 and 120 (Allen 1975).…”

Section: Introductionmentioning

confidence: 99%

The influence of maternal size on placental, fetal and postnatal growth in the horse. II. Endocrinology of pregnancy

Allen

Wilsher²,

Stewart³

et al. 2002

Journal of Endocrinology

View full text Add to dashboard Cite

Within-breed artificial insemination and between-breed embryo transfer were carried out in small pony (P) and large Thoroughbred (Tb) mares to create 4 types of horse pregnancy in which the fetus experienced spatial and nutritional deprivation (Tb-in-P; n=8), luxury (P-in-Tb; n=7) or normality (Tb-in-Tb; n=7 and P-in-P; n=7) in utero.Measurement of equine chorionic gonadotrophin (eCG), total conjugated oestrogens and progestagen concentrations in serial peripheral serum samples recovered from all the mares throughout gestation showed that the amount of eCG produced during the first half of gestation was dependent upon the breed of the mare rather than the breed of the fetus being carried. In contrast, the mean total amounts of oestrogens produced, as measured by area under the curve, were significantly greater (P=0·003) in the two types of pregnancy in which a Thoroughbred fetus was being carried (Tb-in-Tb and Tb-in-P) than those in which a pony fetus was gestated (P-in-P and P-in-Tb); the evidence suggests that the Tb fetus may have larger gonads than the P fetus and thereby secrete more C-19 precursor steroids for aromatisation to oestrogens by the placenta. In the final weeks of pregnancy mean plasma progestagen concentrations rose much earlier, and to significantly higher levels (P<0·001), in the Tb-in-P than in the P-in-Tb pregnancies, thereby reflecting the increased fetal stress in the former causing premature maturation of the fetal adrenal gland. This, in turn, resulted in increased secretion of pregnenolone by the adrenal cortex for conversion to progestagens by the placenta.

show abstract

“…Panarace et al (2006) observaram um grande aumento no volume de sangue após 16 semanas de gestação no lado do corno gestante e um ligeiro aumento do volume de sangue foi observado após 20 semanas no corno contralateral a gestação, como observado no presente estudo, onde foi determinado um aumento na vascularização com o pico máximo na 10ª semana (D70). Clegg et al (1954) demonstraram que os cálices endometriais nas éguas gestantes tem sua produção máxima de eCG aproximadamente entre os dias 60-75 de gestação. Como no presente estudo a avaliação foi feita semanalmente (63-70-77 dias de gestação) igualmente poderia sugerir um aumento da perfusão vas- .…”

Section: Efeito Do Local De Ocorrência Da Gestação E Tempo Da Gestaçãounclassified

Vascularização uterina de éguas prenhes de jumento e de garanhão monitoradas por ultrassonografia Doppler

Lemos

Campos

Ferreira³

et al. 2017

Pesq. Vet. Bras.

View full text Add to dashboard Cite

show abstract

The Endometrial Cups and Allantochorionic Pouches in the Mare With Emphasis on the Source of Equine Gonadotrophin

Cited by 76 publications

References 0 publications

The Influence of Foetal Genotype on Equine Gonadotrophin Secretion

The Influence of Foetal Genotype on Equine Gonadotrophin Secretion

The influence of maternal size on placental, fetal and postnatal growth in the horse. II. Endocrinology of pregnancy

Vascularização uterina de éguas prenhes de jumento e de garanhão monitoradas por ultrassonografia Doppler

Contact Info

Product

Resources

About