The Episiotomy Effect of Topical Combination of Cinnamon Oil and Red Betel on Skin Wound Healing Mechanism

Emelda,; Alfiana, Ratih Devi; Kusumawardani, Nurul; Yolanda,; Widyarini, Sitarina

doi:10.2991/ahsr.k.211105.021

Cited by 3 publications

(1 citation statement)

References 20 publications

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“…In this study it was found that giving red betel leaf ointment was effective in accelerating the healing of perineal wounds degrees 1, 2 and 3 in postpartum mothers less than 7 days after the puerperium and can decrease the possibility of infection. This study is in accordance with several previous studies which stated that red betel leaf compounds were effective in accelerating the healing of perineal wounds after childbirth (Alfiana et al, 2022;Damarini et al, 2013b;Emelda et al, 2021;Kyu et al, 2018;Stianto et al, 2018). It's just that most previous studies used boiled water from red betel leaves and had not yet formed an ointment with a measurable dose for how to use it.…”

Section: Discussionsupporting

confidence: 93%

Analysis of Red Betel Leaf Tests As A Natural Anti-Infection In Post Partum Mothers

Fratidhina¹,

Mulyati

Astri

et al. 2023

women midwives & midwifery

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Background: Incidence of infection contributes to maternal mortality. Innovative efforts to treat infection in postpartum mothers continue to be made, including non-pharmacological techniques. The local wisdom of red betel leaves is believed by the community to be able to handle it. The true efficacy of this extraordinary red betel leaf deserves further investigation. The purpose of this study was to assess the effectiveness of red betel on perineal wound healing in postpartum mothers. Methods: This study used the Quasi Experiment with Control Group Design method. The study was conducted on 80 postpartum mothers with perineal wounds degrees 1 to 3. 40 women were included in the intervention group who were given red betel ointment made by researchers from 2 hours to 7 days postpartum. 40 people as the control group were given perineal wound care according to standard. Assessment of wound healing was carried out every day until the 7th day postpartum. Statistical tests used the dependent and independent t-tests to examine differences in healing scores in the two study groups. Results: There was an increase in the average perineal wound healing value in the intervention group which was higher and there was an increase in the average healing value every day, starting from the first day (mean = 9.25), the second day (mean = 11.55), and the seventh day (mean = 12.65) compared to the control group, p value <0.001. On the third day postpartum, the intervention group had the maximum healing value (100%) compared to the control group (52.5%)

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Section: Discussionsupporting

confidence: 93%

Analysis of Red Betel Leaf Tests As A Natural Anti-Infection In Post Partum Mothers

Fratidhina¹,

Mulyati

Astri

et al. 2023

women midwives & midwifery

View full text Add to dashboard Cite

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Pharmacological Study: Synergistic Antidiabetic Activity of Cinnamon Bark and Zingiber Extract in Streptozotocin-Induced Diabetic Rats

Nurinda

Kusumawardani

Wulandari

et al. 2022

Open Access Maced J Med Sci

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Background: Cinnamon has been widely used by Indonesian people as a complementary therapy to treat hyperglycemia such as in diabetes mellitus patients. While ginger is also used as a mixture in traditional anti hyperglycemia herb. There is not known how much antidiabetic effect of cinnamon ethanolic extract when combined with ginger, and not many studies have analyzed the correlation of lowering blood glucose levels associated with increasing of insulin of this combination. Objectives: This study aimed to investigates antidiabetic activity of cinnamon extract, zingiber extract, and mixture on streptozotocin-induced diabetic rats. Methods: This pharmacological study used Wistar strain male rats under hyperglycemia condition induced by streptozotocin at a dose of 45mg/kg. Sample were grouped with 6 animals in each where there was a positive and negative control group and also an intervention group given ethanol extract for 14 days. Results: The result showed that all intervention groups experienced an increase in insulin levels and a decrease in blood glucose levels after 14 days. The One Way Anova test showed that the increase of insulin levels treated with combination of ethanolic extract cinnamon bark at the dose 150mg/200gr and ginger ethanolic extract at the dose 100mg/200gr was comparable to Glibenclamide (p=0.355), but the decrease in blood glucose levels between groups showed a difference that was not statistically significant. There was a relationship between insulin levels and blood glucose levels linearity with the equation Y (insulin level) = -5.261 + (-0.060) blood glucose level. Conclusions: The combination of cinnamon and ginger showed beneficial synergistic anti-diabetic activity. It can increase insulin levels, making it possible to control blood sugar levels in high blood glucose conditions.

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The Effectiveness of Red Betel Leaf and Cinnamon Oil for Antibacterial and Anti-inflammatory in Perineal Tears: A Scoping Review

Alfiana¹,

Mulyaningsih²,

Emelda

et al. 2022

Open Access Maced J Med Sci

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BACKGROUND: A tear in the perineum experienced by postpartum women can occur due to an episiotomy process or a spontaneous tear. This cloak, in addition to causing curiosity, can also cause infection if not treated or treated appropriately. Based on several research results, the current treatment for perineal tears is the administration of antiseptic, anti-pain, and antibiotics orally or topically. Several Indonesian herbal plants can be used to accelerate the healing of torn wounds in the perineum due to the ability of these plants as antibacterial and anti-inflammatory. These plants include red betel leaf and cinnamon oil. AIM: The objective of the study was to review the literature from research results that discuss the activity of red betel leaf and cinnamon oil as antibacterial and anti-inflammatory both orally and topically. SEARCH METHOD: Searching for articles through databases on Google Scholar, in the past years, that is, 2008–2021. INCLUSION: Review articles involving research on experimental animals with in vitro and in vivo activity tests using the Completely Randomized Design method. RESULTS: As well as, 12 relevant articles showed that both red betel leaf and cinnamon oil were tested in vitro and in vivo, showing that these two plants effectively act as antibacterial and anti-inflammatory. CONCLUSION: Two herbal plants red betel leaf and cinnamon oil have the potential to treat and accelerate the healing of perineal tears through their antibacterial and anti-inflammatory activities.

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The Episiotomy Effect of Topical Combination of Cinnamon Oil and Red Betel on Skin Wound Healing Mechanism

Cited by 3 publications

References 20 publications

Analysis of Red Betel Leaf Tests As A Natural Anti-Infection In Post Partum Mothers

Analysis of Red Betel Leaf Tests As A Natural Anti-Infection In Post Partum Mothers

Pharmacological Study: Synergistic Antidiabetic Activity of Cinnamon Bark and Zingiber Extract in Streptozotocin-Induced Diabetic Rats

The Effectiveness of Red Betel Leaf and Cinnamon Oil for Antibacterial and Anti-inflammatory in Perineal Tears: A Scoping Review

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