The ESIPT fluorescent probes for N2H4 based on benzothiazol and their applications for gas sensing and bioimaging

Recently, the design, synthesis and development of chemodosimeters for hydrazine with high selectivity and sensitivity has attracted tremendous attention due to its major contributions to human health and disease including applications in various platforms. In this review, we recapitulate different strategies for the design of reaction‐based colorimetric and fluorometric probes for the detection of hydrazine and their applications in hydrazine sensing in living systems. The sensing strategies for hydrazine have been divided into six categories: (a) cleavage of the acetoxy group; (b) the nucleophilic addition‐elimination on keto ester; (c) the nucleophilic substitution‐elimination to tandem cyclization on halo‐ester; (d) the nucleophilic addition reaction to phthalimide derivative to phthalhydrazide; (e) the chemical displacement of active methylene compound to hydrazone derivative and (f) Other different approaches. Additionally, a variety of techniques have been devised here for the detection of hydrazine over other comparable ions and neutral amines.

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“…Chen et al . designed two ESIPT based probes 18 and 19 for micromolar detection of hydrazine in solution as well as in live samples (Figure ).…”

Section: Introductionmentioning

confidence: 99%

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

Manna¹,

Gangopadhyay

Maiti

et al. 2019

ChemistrySelect

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“…Many N2H4 fluorescent probes were used to detect N2H4 in water, but the fluorescent probes, which have different natural light visible colorimetric responses to different low concentrations of N2H4, were still very deficient (Table S2, Supporting Information). [31][32][33][34][35][36] From the LOD, the calibration range and the stokes shift aspects, the analytical performances of Probe 1 as a fluorescent reagent were weak. However, the most recommendable aspect of Probe 1 is that it has different natural light visible colorimetric responses to different low concentrations of N2H4.…”

Section: Resultsmentioning

confidence: 99%

A Natural Light Visible Colorimetric Responses Fluorescent Probe for Hydrazine Detection

Yang

et al. 2019

ANAL. SCI.

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A natural light visible colorimetric responses fluorescent probe (Probe 1) was developed for N2H4 detection. The recognition mechanism of Probe 1 for hydrazine is based on addition-cyclization. The LOD of Probe 1 for N2H4 was 80.3 nM (0.0026 mg/L), which is below the national limited standard (0.02 mg/L). When various concentrations of N2H4 were added, the color of the Probe 1 solution was graded gradually from yellow to colorless, which could be observed under natural light. The changing course only takes 5 min. Furthermore, Probe 1 was successful applied to detect N2H4 in mineral water, seawater, tap water and river water. The obtained recovery ranged from 91.91-100.00%. Probe 1 has great potential, developed as a visual tool for N2H4 rapid detection.

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“…Heteroaromatic benzothiazole derivatives are well-studied compounds, due in the main to their various and useful biological activities (for a review, see Gulati et al, 2017), but also to their fluorescent and optical properties (e.g. Liu et al, 2018). Hydrazonyl derivatives, 2-Ar-CH N-NH-benzothiazoles, formed from 2-hydrazinylbenzothiazole and ArCHO have attracted attention: for example, Katava et al (2017) have reported antitumor activities and Behera & Manivannan (2017) studied their use as sensors.…”

Section: Chemical Contextmentioning

confidence: 99%

Expected and unexpected products of reactions of 2-hydrazinylbenzothiazole with 3-nitrobenzenesulfonyl chloride in different solvents

Morscher¹,

Souza²,

Wardell³

et al. 2018

Acta Cryst E

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The ESIPT fluorescent probes for N2H4 based on benzothiazol and their applications for gas sensing and bioimaging

Cited by 69 publications

References 38 publications

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

Recent Developments in Fluorometric and Colorimetric Chemodosimeters Targeted towards Hydrazine Sensing: Present Success and Future Possibilities

A Natural Light Visible Colorimetric Responses Fluorescent Probe for Hydrazine Detection

Expected and unexpected products of reactions of 2-hydrazinylbenzothiazole with 3-nitrobenzenesulfonyl chloride in different solvents

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